Wilmer Eye Institute, The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Department of Biostatistics, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA.
Am J Ophthalmol. 2019 Dec;208:234-241. doi: 10.1016/j.ajo.2019.08.009. Epub 2019 Aug 26.
To examine associations between near vision impairment (NVI) and frailty.
Cross-sectional study.
Setting: Nationally representative sample of noninstitutionalized United States civilians.
Total of 2705 older adults aged ≥60 years from National Health and Nutrition Examination Survey (1999-2002).
Presenting NVI (PNVI): near acuity worse than 20/40. Self-reported NVI (SNVI): self-reported difficulty with near vision tasks.
MAIN OUTCOME MEASURE(S): Five-item physical frailty index; participants classified as frail (≥3 criteria) and prefrail (1 or 2 criteria). Propensity score-adjusted and probability-weighted multinomial multivariable logistic regression was used to examine associations of PNVI and SNVI with frailty.
Of 2705 participants, 381 (10%), 160 (5%), and 106 (3%) had PNVI only, SNVI only, and PNVI+SNVI, respectively. In fully adjusted models, as compared to those without PNVI, participants with PNVI were more likely to be prefrail (odds ratio [OR] = 1.6; 95% confidence interval [CI] = 1.1, 2.3) and frail (OR = 2.5; 95% CI = 1.4, 4.3). As compared to those without SNVI, participants with SNVI were more likely to be prefrail (OR = 2.9; 95% CI = 1.8, 4.7) and frail (OR = 4.3; 95% CI = 2.2, 8.3). As compared to those without PNVI or SNVI, participants with PNVI+SNVI were more likely to be prefrail and frail (prefrail: OR = 4.0; 95% CI = 2.2, 7.2 and frail: OR = 4.5; 95% CI = 1.7,12.7).
Older adults with PNVI and SNVI were more likely to be prefrail and frail than those without respective NVI, suggesting that NVI is associated with frailty.
探讨视力近距离损伤(NVI)与虚弱之间的关联。
横断面研究。
研究地点:美国全国代表性的非机构化平民样本。
共有 2705 名年龄≥60 岁的老年人,来自全国健康和营养检查调查(1999-2002 年)。
存在视力近距离损伤(PNVI):近视力差于 20/40。自我报告的视力近距离损伤(SNVI):自我报告的近距离视力任务困难。
五项目身体虚弱指数;将参与者分为虚弱(≥3 项标准)和虚弱前期(1 或 2 项标准)。采用倾向评分调整和概率加权多项多变量逻辑回归来检验 PNVI 和 SNVI 与虚弱的关系。
在 2705 名参与者中,分别有 381 名(10%)、160 名(5%)和 106 名(3%)仅有 PNVI、仅有 SNVI 和同时有 PNVI+SNVI。在完全调整的模型中,与没有 PNVI 的参与者相比,有 PNVI 的参与者更有可能处于虚弱前期(优势比[OR]为 1.6;95%置信区间[CI]为 1.1,2.3)和虚弱(OR 为 2.5;95%CI 为 1.4,4.3)。与没有 SNVI 的参与者相比,有 SNVI 的参与者更有可能处于虚弱前期(OR 为 2.9;95%CI 为 1.8,4.7)和虚弱(OR 为 4.3;95%CI 为 2.2,8.3)。与没有 PNVI 或 SNVI 的参与者相比,同时有 PNVI+SNVI 的参与者更有可能处于虚弱前期和虚弱状态(虚弱前期:OR 为 4.0;95%CI 为 2.2,7.2;虚弱:OR 为 4.5;95%CI 为 1.7,12.7)。
与没有相应 NVI 的老年人相比,有 PNVI 和 SNVI 的老年人更有可能处于虚弱前期和虚弱状态,这表明 NVI 与虚弱有关。