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基于高速光学相干断层扫描的眼生物测量仪与吹气系统相结合,用于测定无诱导回缩的眼动态。

High-speed OCT-based ocular biometer combined with an air-puff system for determination of induced retraction-free eye dynamics.

作者信息

Jiménez-Villar Alfonso, Mączyńska Ewa, Cichański Artur, Wojtkowski Maciej, Kałużny Bartłomiej J, Grulkowski Ireneusz

机构信息

Institute of Physics, Faculty of Physics, Astronomy and Informatics, Nicolaus Copernicus University, ul. Grudziądzka 5, 87-100 Toruń, Poland.

Institute of Mechanics and Machine Design, Faculty of Mechanical Engineering, UTP University of Science and Technology, Al. Prof. S. Kaliskiego 7, 85-796 Bydgoszcz, Poland.

出版信息

Biomed Opt Express. 2019 Jun 27;10(7):3663-3680. doi: 10.1364/BOE.10.003663. eCollection 2019 Jul 1.

Abstract

We demonstrate a swept source OCT-based ocular biometer integrated with an air-puff stimulus to study the reaction of the eye to mechanical stimulation . The system enables simultaneous measurement of the stimulus strength and high-speed imaging of the eye dynamics along the visual axis. We characterize the stimulus and perform optimization of the data acquisition for a proper interpretation of the results. Access to the dynamics of axial eye length allows for a determination of the eye retraction, which is used to correct the air-puff induced displacement of ocular structures. We define the parameters to quantify the reaction of the eye to the air puff and determine their reproducibility in a group of healthy subjects. We observe the corneal deformation process and axial wobbling of the crystalline lens. OCT biometer combined with the air puff is the first instrument with the potential to provide comprehensive information on the biomechanics of ocular components.

摘要

我们展示了一种基于扫频源光学相干断层扫描(OCT)的眼生物测量仪,该仪器集成了吹气刺激,用于研究眼睛对机械刺激的反应。该系统能够同时测量刺激强度,并沿视轴对眼睛动态进行高速成像。我们对刺激进行了表征,并对数据采集进行了优化,以便对结果进行恰当解读。获取眼轴长度的动态信息有助于确定眼球后缩情况,这可用于校正吹气引起的眼部结构位移。我们定义了量化眼睛对吹气反应的参数,并确定了它们在一组健康受试者中的可重复性。我们观察到了角膜变形过程和晶状体的轴向摆动。结合吹气功能的OCT生物测量仪是首个有潜力提供眼部各组成部分生物力学综合信息的仪器。

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