Juvenile myoclonic epilepsy (JME) may be linked to the BF and HLA loci on human chromosome 6.
作者信息
Greenberg D A, Delgado-Escueta A V, Widelitz H, Sparkes R S, Treiman L, Maldonado H M, Park M S, Terasaki P I
机构信息
Comprehensive Epilepsy Program, VA Medical Center West Los Angeles 90073.
出版信息
Am J Med Genet. 1988 Sep;31(1):185-92. doi: 10.1002/ajmg.1320310125.
PMID:3146924
Abstract
Although certain forms of epilepsy have long been suspected to be inherited, heterogeneity has made it difficult to find the genes responsible for any subtypes. We found that families ascertained through patients with juvenile myoclonic epilepsy show linkage with the BF and HLA loci on human chromosome 6. There is some evidence that the locus may be outside the HLA complex and no evidence as yet of an association with any allele of the HLA complex.
摘要
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