[I期非小细胞肺癌的立体定向放射治疗。2019年的现状及建议:立体定向放射治疗能否替代手术?]
[Stereotactic radiotherapy of stage I non-small cell lung cancer. State of the art in 2019 and recommendations: Stereotaxy as an alternative to surgery?].
作者信息
Kaiss H, Mornex F
机构信息
Département de radiothérapie oncologie, centre hospitalier Lyon-Sud, 165, chemin du Grand-Revoyet, 69495 Pierre-Bénite cedex, France.
出版信息
Cancer Radiother. 2019 Oct;23(6-7):720-731. doi: 10.1016/j.canrad.2019.07.132. Epub 2019 Aug 27.
Stereotactic radiotherapy (or Stereotactic body radiotherapy [SBRT]) is a technique currently well established in the therapeutic arsenal for the management of bronchial cancers. It represents the standard treatment for inoperable patients or who refuses surgery. It is well tolerated, especially in elderly and frail patients, and the current issue is to define its indications in operated patients, based on retrospective and randomized trials comparing stereotactic radiotherapy and surgery, with results equivalents. This work analyzes in detail the different aspects of pulmonary stereotactic radiotherapy and suggests arguments that help in the therapeutic choice between surgery and stereotaxic irradiation. In all cases, the therapeutic decision must be discussed in a multidisciplinary consultation meeting, while informing the patient of the possible therapeutic options.
立体定向放射治疗(或立体定向体部放射治疗[SBRT])是目前在支气管癌治疗手段中已确立的一种技术。它是无法手术或拒绝手术患者的标准治疗方法。其耐受性良好,尤其是对老年体弱患者,目前的问题是根据比较立体定向放射治疗与手术的回顾性和随机试验结果相当,来确定其在接受手术患者中的适应症。这项工作详细分析了肺部立体定向放射治疗的不同方面,并提出有助于在手术和立体定向照射之间做出治疗选择的论据。在所有情况下,治疗决策都必须在多学科会诊会议上进行讨论,同时告知患者可能的治疗选择。