Yossi S, Nguyen D, Krhili S, Lizée T, Khodri M
ORLAM, centre de radiothérapiede l'ouest lyonnais Charcot, 11, avenue Maréchal-Foch, 69110 Sainte-Foy-Lès, Lyon, France; ORLAM, centre de radiothérapie Mermoz, Lyon, France; ORLAM, centre de radiothérapie et oncologie, Macon, France; ORLAM, centre de radiothérapie Bayard, Villeurbanne, France.
ORLAM, centre de radiothérapiede l'ouest lyonnais Charcot, 11, avenue Maréchal-Foch, 69110 Sainte-Foy-Lès, Lyon, France; ORLAM, centre de radiothérapie Mermoz, Lyon, France; ORLAM, centre de radiothérapie et oncologie, Macon, France; ORLAM, centre de radiothérapie Bayard, Villeurbanne, France.
Cancer Radiother. 2020 Jun;24(3):267-274. doi: 10.1016/j.canrad.2019.11.002. Epub 2020 Mar 16.
Lung cancer is the fourth most common cancer in France with a prevalence of 30,000 new cases per year. Lobectomy surgery with dissection is the gold standard treatment for T1-T2 localized non-small cell lung carcinoma. A segmentectomy may be proposed to operable patients but fragile from a respiratory point of view. For inoperable patients or patients with unsatisfactory pulmonary function tests, local treatment with stereotactic radiotherapy may be proposed to achieve local control rates ranging from 85 to 95% at 3-5 years. Several studies have examined prognostic factors after stereotaxic pulmonary radiotherapy. We conducted a general review of the literature to identify factors affecting local control.
肺癌是法国第四大常见癌症,每年新增病例达30000例。肺叶切除加淋巴结清扫术是T1-T2期局限性非小细胞肺癌的金标准治疗方法。对于可手术但从呼吸角度来看身体较为虚弱的患者,可考虑行肺段切除术。对于无法手术或肺功能测试结果不理想的患者,可采用立体定向放射治疗进行局部治疗,3至5年的局部控制率可达85%至95%。多项研究探讨了立体定向肺部放疗后的预后因素。我们对文献进行了全面综述,以确定影响局部控制的因素。