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本文引用的文献

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Effects of Tumor Necrosis Factor Blocker on Salicylate-Induced Tinnitus in Mice.肿瘤坏死因子阻滞剂对小鼠水杨酸盐诱导耳鸣的影响
Int Tinnitus J. 2017 Jun 1;21(1):24-29. doi: 10.5935/0946-5448.20170006.
2
Neural substrates predicting short-term improvement of tinnitus loudness and distress after modified tinnitus retraining therapy.预测经改良耳鸣再训练疗法治疗后耳鸣响度和困扰短期改善的神经基础。
Sci Rep. 2016 Jul 6;6:29140. doi: 10.1038/srep29140.
3
Characteristics and Spontaneous Recovery of Tinnitus Related to Idiopathic Sudden Sensorineural Hearing Loss.特发性突发性感音神经性听力损失相关耳鸣的特征及自然恢复情况
Otol Neurotol. 2016 Jul;37(6):634-41. doi: 10.1097/MAO.0000000000001081.
4
Human Auditory and Adjacent Nonauditory Cerebral Cortices Are Hypermetabolic in Tinnitus as Measured by Functional Near-Infrared Spectroscopy (fNIRS).通过功能近红外光谱(fNIRS)测量发现,耳鸣患者的人类听觉及相邻非听觉大脑皮层代谢亢进。
Neural Plast. 2016;2016:7453149. doi: 10.1155/2016/7453149. Epub 2016 Mar 2.
5
Clinical trial on tonal tinnitus with tailor-made notched music training.定制化窄带音乐训练治疗音调性耳鸣的临床试验
BMC Neurol. 2016 Mar 17;16:38. doi: 10.1186/s12883-016-0558-7.
6
A Systematic Review and Meta-Analysis on the Association between Hypertension and Tinnitus.高血压与耳鸣关联的系统评价与荟萃分析
Int J Hypertens. 2015;2015:583493. doi: 10.1155/2015/583493. Epub 2015 Dec 31.
7
The effectiveness of acupuncture as a treatment for tinnitus: a randomized controlled trial using (99m)Tc-ECD SPECT.针刺疗法治疗耳鸣的有效性:一项使用(99m)Tc-ECD单光子发射计算机断层扫描的随机对照试验。
Eur Radiol. 2016 Sep;26(9):3234-42. doi: 10.1007/s00330-015-4164-7. Epub 2016 Jan 8.
8
Expression of Antioxidant Genes in the Mouse Cochlea and Brain in Salicylate-Induced Tinnitus and Effect of Treatment with Spirulina platensis Water Extract.水杨酸诱导耳鸣小鼠耳蜗和脑中抗氧化基因的表达及钝顶螺旋藻水提取物的治疗作用
Audiol Neurootol. 2015;20(5):322-9. doi: 10.1159/000381934. Epub 2015 Aug 5.
9
[The clinical efficacy of composite acoustic therapy in patients of sudden deafness with tinnitus].[复合声疗法对突发性聋伴耳鸣患者的临床疗效]
Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2015 Feb;29(4):330-3.
10
Analysis of the prevalence and associated risk factors of tinnitus in adults.成人耳鸣患病率及相关危险因素分析
PLoS One. 2015 May 28;10(5):e0127578. doi: 10.1371/journal.pone.0127578. eCollection 2015.

三联疗法治疗慢性耳鸣的疗效。

Outcomes of Triple-Combination Therapy for Chronic Tinnitus.

机构信息

Department of Traditional Chinese Medicine, Dalin Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Chiayi, Taiwan, R.O.C.

Graduate Institute of Integrated Medicine, College of Chinese Medicine, China Medical University, Taichung, Taiwan, R.O.C.

出版信息

In Vivo. 2019 Sep-Oct;33(5):1707-1712. doi: 10.21873/invivo.11660.

DOI:10.21873/invivo.11660
PMID:31471428
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6755017/
Abstract

BACKGROUND/AIM: Patients with tinnitus suffer not only from auditory dysfunction but also physical, mental, and social difficulties. Our aim was to investigate the outcomes of our triple-combination therapy for chronic tinnitus, which includes narrow-band noise masking, auricular acupuncture and cognitive behavioral therapy.

PATIENTS AND METHODS

The tinnitus handicap inventory (THI) scores of 78 adults with chronic tinnitus who received triple-combination therapy for 12 weeks were analyzed retrospectively.

RESULTS

There were 39 females and 39 males in this study. The mean age was 60.5 years [standard deviation (SD)=13.0, range=27-88 years] for all subjects. Mean pure tone average=39.5 decibel hearing level (SD=23.09). Pre-treatment mean THI score was 41.4 (SD=21.13), functional (F) subscore was 17.9 (SD=10.69), emotional (E) subscore was 10.6 (SD=6.87), and catastrophic (C) subscore was 12.9 (SD=4.85). Post-treatment THI total score was significantly lower compared to pre-treatment THI total score. Also, post-treatment subscores were significantly lower compared to pre-treatment subscores in F and C subsocres, but not in E subscore. In addition, multivariate logistic regression analysis showed that coffee and tea consumption was significantly positively associated with a reduction of THI total score.

CONCLUSION

Triple-combination therapy could be helpful for chronic tinnitus patients. It seemed that coffee and tea consumption may elicit increased improvement in conjunction with combined therapy for chronic tinnitus.

摘要

背景/目的:患有耳鸣的患者不仅遭受听觉功能障碍,还遭受身体、心理和社会困难。我们的目的是调查我们的慢性耳鸣三联疗法的结果,该疗法包括窄带噪声掩蔽、耳针和认知行为疗法。

患者和方法

回顾性分析了 78 名接受三联疗法治疗 12 周的慢性耳鸣成人患者的耳鸣残疾量表(THI)评分。

结果

本研究中共有 39 名女性和 39 名男性,所有受试者的平均年龄为 60.5 岁[标准差(SD)=13.0,范围 27-88 岁]。平均纯音平均=39.5 分贝听力水平(SD=23.09)。治疗前 THI 总分为 41.4(SD=21.13),功能(F)子分为 17.9(SD=10.69),情感(E)子分为 10.6(SD=6.87),灾难性(C)子分为 12.9(SD=4.85)。治疗后 THI 总分明显低于治疗前 THI 总分。此外,治疗后 F 和 C 子评分明显低于治疗前子评分,但 E 子评分则不然。此外,多元逻辑回归分析表明,咖啡和茶的消费与 THI 总分的降低呈显著正相关。

结论

三联疗法对慢性耳鸣患者可能有帮助。似乎咖啡和茶的消费可能会增加与慢性耳鸣联合治疗的改善。