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成人耳鸣患病率及相关危险因素分析

Analysis of the prevalence and associated risk factors of tinnitus in adults.

作者信息

Kim Hyung-Jong, Lee Hyo-Jeong, An Soo-Youn, Sim Songyong, Park Bumjung, Kim Si Whan, Lee Joong Seob, Hong Sung Kwang, Choi Hyo Geun

机构信息

Department of Otorhinolaryngology-Head & Neck Surgery, Hallym University Sacred Heart Hospital, Anyang, Korea.

Department of Otorhinolaryngology-Head & Neck Surgery, Thyroid/Head & Neck Cancer Center of the Dongnam Institute of Radiological & Medical Sciences (DIRAMS), Busan, Korea.

出版信息

PLoS One. 2015 May 28;10(5):e0127578. doi: 10.1371/journal.pone.0127578. eCollection 2015.

Abstract

BACKGROUND

Tinnitus is a common condition in adults; however, the pathophysiology of tinnitus remains unclear, and no large population-based study has assessed the associated risk factors. The aim of this study was to analyze the prevalence and associated risk factors of tinnitus.

METHODS

We conducted a cross-sectional study using data from the Korea National Health and Nutrition Examination Survey, with 19,290 participants ranging in age from 20 to 98 years old, between 2009 and 2012. We investigated the prevalence of tinnitus using a questionnaire and analyzed various possible factors associated with tinnitus using simple and multiple logistic regression analysis with complex sampling.

RESULTS

The prevalence of tinnitus was 20.7%, and the rates of tinnitus associated with no discomfort, moderate annoyance, and severe annoyance were 69.2%, 27.9%, and 3.0%, respectively. The prevalence of tinnitus and the rates of annoying tinnitus increased with age. The adjusted odds ratio (AOR) of tinnitus was higher for females, those with a smoking history, those reporting less sleep (≤ 6 h), those with more stress, those in smaller households, those with a history of hyperlipidemia osteoarthritis, rheumatoid arthritis, asthma, depression, thyroid disease, an abnormal tympanic membrane, unilateral hearing loss, bilateral hearing loss, noise exposure from earphones, noise exposure at the workplace, noise exposure outside the workplace, and brief noise exposure. Additionally, unemployed individuals and soldiers had higher AORs for tinnitus. The AOR of annoying tinnitus increased with age, stress, history of hyperlipidemia, unilateral hearing loss, and bilateral hearing loss.

CONCLUSIONS

Tinnitus is very common in the general population and is associated with gender, smoking, stress, sleep, hearing loss, hyperlipidemia, osteoarthritis, rheumatoid arthritis, asthma, depression, and thyroid disease history.

摘要

背景

耳鸣在成年人中是一种常见病症;然而,耳鸣的病理生理学仍不清楚,且尚无基于大规模人群的研究评估其相关危险因素。本研究旨在分析耳鸣的患病率及相关危险因素。

方法

我们利用韩国国家健康与营养检查调查的数据进行了一项横断面研究,研究对象为2009年至2012年间年龄在20至98岁的19290名参与者。我们通过问卷调查来调查耳鸣的患病率,并使用简单和多重逻辑回归分析及复杂抽样来分析与耳鸣相关的各种可能因素。

结果

耳鸣的患病率为20.7%,与无不适、中度困扰和重度困扰相关的耳鸣发生率分别为69.2%、27.9%和3.0%。耳鸣的患病率及令人烦恼的耳鸣发生率随年龄增长而增加。女性、有吸烟史者、报告睡眠较少(≤6小时)者、压力较大者、家庭规模较小者、有高脂血症、骨关节炎、类风湿关节炎、哮喘、抑郁症、甲状腺疾病史者、鼓膜异常者、单侧听力损失者、双侧听力损失者、耳机噪音暴露者、工作场所噪音暴露者、工作场所以外噪音暴露者以及短暂噪音暴露者的耳鸣调整优势比(AOR)较高。此外,失业者和军人的耳鸣AOR也较高。令人烦恼的耳鸣的AOR随年龄、压力、高脂血症病史、单侧听力损失和双侧听力损失而增加。

结论

耳鸣在普通人群中非常常见,且与性别、吸烟、压力、睡眠、听力损失、高脂血症、骨关节炎、类风湿关节炎、哮喘、抑郁症及甲状腺疾病史有关。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f41e/4447366/43de83ce53ba/pone.0127578.g001.jpg

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