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腺样体赘生物中的淋巴细胞:与血液淋巴细胞相比的体外增殖反应。

Lymphocytes from adenoid vegetations: proliferative responses in vitro as compared to blood lymphocytes.

作者信息

Mogensen H H, Meistrup-Larsen K I, Andersen V

出版信息

Acta Pathol Microbiol Scand C. 1979 Jun;87C(3):197-202.

PMID:314723
Abstract

Thymidine incorporation by lymphocytes obtained from adenoids (AVL) and blood (PBL) were compared in 27 children undergoing adenoidectomy. Optimal conditions as regards cell number and duration of culture were worked out. The spontaneous thymidine incorporation was higher in PBL than in AVL. In cultures stimulated by polyclonal activators or by PPD, the responses of PBL were higher. The dose-response curves for PBL and AVL after stimulation with killed H. influenzae were different: PBL showed a higher response, the optimal antigen concentration was lower for PBL, and the responsiveness to suboptimal antigen concentrations wash higher in PBL than in AVL.

摘要

对27例接受腺样体切除术的儿童,比较了从腺样体(AVL)和血液(PBL)中获取的淋巴细胞的胸腺嘧啶核苷掺入情况。确定了细胞数量和培养持续时间方面的最佳条件。PBL中的自发胸腺嘧啶核苷掺入高于AVL。在由多克隆激活剂或PPD刺激的培养物中,PBL的反应更高。用灭活的流感嗜血杆菌刺激后,PBL和AVL的剂量反应曲线不同:PBL显示出更高的反应,PBL的最佳抗原浓度更低,并且PBL对次优抗原浓度的反应性高于AVL。

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Acta Pathol Microbiol Scand C. 1979 Jun;87C(3):197-202.
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