Rynnel-Dagöö B, Möller E, Waterfield E
Clin Exp Immunol. 1977 Mar;27(3):425-31.
Adenoid lymphocytes from children undergoing adenoidectomy were compared with blood cells from the same children using techniques for identifying T cells and B cells. A high proportion of adenoid lymphocytes were immunoglobulin positive cells. Of these only a minor fraction carried receptors for the Fc part of IgG. Adenoid B lymphocytes respond poorly if at all to polyclonal B-cell activators, such as LPS or PPD, which show a different reactivity compared to human splenic cells. The response to anti B2-microglobulin was also different; blood cells responded better than adenoid cells. Thus distinct subpopulations of B lymphocytes reside in different lymphoid organs. The adenoid lymphocyte reactivity might reflect their function in the defence mechanism against infections.
采用鉴定T细胞和B细胞的技术，对接受腺样体切除术的儿童的腺样体淋巴细胞与同一儿童的血细胞进行了比较。腺样体淋巴细胞中有很大比例是免疫球蛋白阳性细胞。其中只有一小部分带有IgG Fc部分的受体。腺样体B淋巴细胞对多克隆B细胞激活剂（如LPS或PPD）反应很差，甚至无反应，与人类脾细胞相比，其反应性不同。对抗B2微球蛋白的反应也不同；血细胞的反应比腺样体细胞更好。因此，B淋巴细胞的不同亚群存在于不同的淋巴器官中。腺样体淋巴细胞的反应性可能反映了它们在抗感染防御机制中的功能。
