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快速定性二维超声场声空化增强成像测绘。

Fast qualitative two-dimensional mapping of ultrasound fields with acoustic cavitation-enhanced ultrasound imaging.

机构信息

Department of Biomedical Engineering, Columbia University, New York, New York 10027,

出版信息

J Acoust Soc Am. 2019 Aug;146(2):EL158. doi: 10.1121/1.5122194.

DOI:10.1121/1.5122194
PMID:31472567
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6863696/
Abstract

Characterization of ultrasound fields is a routine procedure for both diagnostic and therapeutic ultrasound. Quantitative field mapping with a calibrated hydrophone and multi-axis positioning system can be difficult and time consuming. In this study, the use of acoustic cavitation field mapping as a qualitative surrogate to acoustic pressure field mapping, albeit without acoustic pressure values is demonstrated. This technique allows for fast qualitative mapping of ultrasound fields and thereby functionality of the corresponding transducers, in a matter of seconds. In addition, this technique could be used to rapidly image in vivo acoustic cavitation fields during therapeutic ultrasound applications.

摘要

超声场的特性描述是诊断和治疗超声的常规程序。使用校准的水听器和多轴定位系统进行定量场测绘可能既困难又耗时。在这项研究中,展示了将声空化场测绘用作声压场测绘的定性替代方法,尽管没有声压值。该技术允许在几秒钟内快速定性地绘制超声场,从而可以快速检查相应换能器的功能。此外,该技术可用于在治疗性超声应用期间快速成像体内声空化场。

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本文引用的文献

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Modulation of Brain Function and Behavior by Focused Ultrasound.聚焦超声对脑功能和行为的调节作用
Curr Behav Neurosci Rep. 2018 Jun;5(2):153-164. doi: 10.1007/s40473-018-0156-7. Epub 2018 May 9.
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Visualization of the Intensity Field of a Focused Ultrasound Source In Situ.聚焦超声换能器声场可视化的现场研究。
IEEE Trans Med Imaging. 2019 Jan;38(1):124-133. doi: 10.1109/TMI.2018.2857481. Epub 2018 Jul 19.
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Power cavitation-guided blood-brain barrier opening with focused ultrasound and microbubbles.超声聚焦联合微泡实现的声动力空化引导血脑屏障开放。
Phys Med Biol. 2018 Mar 15;63(6):065009. doi: 10.1088/1361-6560/aab05c.
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4D microvascular imaging based on ultrafast Doppler tomography.基于超快多普勒断层扫描的4D微血管成像。
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Cavitation-enhanced nonthermal ablation in deep brain targets: feasibility in a large animal model.深部脑靶点的空化增强非热消融:大型动物模型中的可行性
J Neurosurg. 2016 May;124(5):1450-9. doi: 10.3171/2015.4.JNS142862. Epub 2015 Sep 18.
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3D ultrafast ultrasound imaging in vivo.体内三维超快超声成像
Phys Med Biol. 2014 Oct 7;59(19):L1-L13. doi: 10.1088/0031-9155/59/19/L1. Epub 2014 Sep 10.
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Three-dimensional transcranial ultrasound imaging of microbubble clouds using a sparse hemispherical array.使用稀疏半球形阵列对微泡云进行三维经颅超声成像。
IEEE Trans Biomed Eng. 2014 Apr;61(4):1285-94. doi: 10.1109/TBME.2014.2300838.
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Ultrafast imaging in biomedical ultrasound.生物医学超声中的超快成像。
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