State Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing 210009, China.
State Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing 210009, China.
Chin J Nat Med. 2019 Aug;17(8):561-574. doi: 10.1016/S1875-5364(19)30058-5.
The shrub Microcos paniulata (MPL; Tiliaceae), distributed in south China, south and southeast Asia, yields a phytomedicine used to treat heat stroke, fever, dyspepsia, diarrhea, insect bites and jaundice. Phytochemical investigations on different parts of MPL indicate the presence of flavonoids, alkaloids, triterpenoids and organic acids. The MPL leaves, fruits, barks and roots extracts showed antidiarrheal, antimicrobial and insecticidal, anti-inflammation, hepatoprotective, cardiovascular protective, blood lipids reducing, analgesic, jaundice-relieving and antipyretic activities, etc. The review aims to summary the traditional uses, botany, phytochemistry, pharmacological bioactivity, quality control, toxicology and potential mechanisms of MPL. Additionally, this review will highlight the existing research gaps in knowledge and provide a foundation for further investigations on this plant.
灌木黄杨叶 Microcos paniulata（MPL；椴树科）分布于中国南方、南亚和东南亚，其植物药被用于治疗中暑、发热、消化不良、腹泻、虫咬和黄疸。对 MPL 不同部位的植物化学研究表明，其含有黄酮类、生物碱、三萜类和有机酸。MPL 的叶、果、皮和根提取物具有抗腹泻、抗菌和杀虫、抗炎、保肝、心血管保护、降血脂、镇痛、退黄和退热等作用。综述旨在总结 MPL 的传统用途、植物学、植物化学、药理学活性、质量控制、毒理学和潜在作用机制。此外，本综述还将突出目前知识领域的研究空白，并为进一步研究该植物提供基础。
