胆道与原发性肝脏肿瘤：何人、何物及为何？

Biliary Tract and Primary Liver Tumors: Who, What, and Why?

作者信息

Hemming Alan W

机构信息

Department of Surgery, University of Iowa, University of Iowa Hospitals & Clinics, 200 Hawkins Drive, SE427 GH, Iowa City, IA 52242, USA.

出版信息

Surg Oncol Clin N Am. 2019 Oct;28(4):519-538. doi: 10.1016/j.soc.2019.06.012.

DOI:10.1016/j.soc.2019.06.012

PMID:31472904

Abstract

Biliary tract and primary liver tumors can be divided into intrahepatic and extrahepatic sites. Hepatocellular carcinoma (HCC) and intrahepatic cholangiocarcinoma are the most common primary liver malignancies, making up 75% and 15% of cases, respectively. In the United States, there has been an increase in incidence of HCC and cholangiocarcinoma over the last 2 decades, and it is probable that the incidence of both will continue to climb. Gallbladder cancer, however, is the most frequent biliary tract cancer, comprising 80% to 90% of biliary tract cancers worldwide. Underlying epidemiology and cause are discussed.

摘要

胆道和原发性肝脏肿瘤可分为肝内和肝外部位。肝细胞癌（HCC）和肝内胆管癌是最常见的原发性肝脏恶性肿瘤，分别占病例的75%和15%。在美国，过去20年中HCC和胆管癌的发病率有所上升，而且两者的发病率可能会继续攀升。然而，胆囊癌是最常见的胆道癌，占全球胆道癌的80%至90%。本文将讨论其潜在的流行病学和病因。