Krampitz Geoffrey W, Aloia Thomas A
Department of Surgery, Thomas Jefferson University, 1015 Walnut Street, Curtis Building, Suite 620, Philadelphia, PA 19107, USA.
Department of Surgical Oncology, University of Texas, MD Anderson Cancer Center, 1440 Pressler Street, Unit 1484, Houston, TX 77030, USA.
Surg Oncol Clin N Am. 2019 Oct;28(4):663-683. doi: 10.1016/j.soc.2019.06.007.
Hepatobiliary malignancies are a diverse group of neoplasms involving the liver, gallbladder, and bile ducts. Although intrahepatic cholangiocarcinoma, perihilar cholangiocarcinoma, hepatocellular carcinoma, and gallbladder adenocarcinoma share many biological and anatomic features, they have distinct clinical presentations and natural histories that require individual consideration. Here, we discuss the incidence, outcomes, patient presentation, initial workup, pathologic diagnoses, staging classification, imaging and surgical staging, and determinants of resectability for each malignancy.
肝胆恶性肿瘤是一组涉及肝脏、胆囊和胆管的多种肿瘤。尽管肝内胆管癌、肝门周围胆管癌、肝细胞癌和胆囊腺癌有许多生物学和解剖学特征，但它们有不同的临床表现和自然病程，需要分别考虑。在此，我们讨论每种恶性肿瘤的发病率、预后、患者表现、初始检查、病理诊断、分期分类、影像学和手术分期以及可切除性的决定因素。
