Carvalho Silva Daniela Marisa, Braga Ana, de Jesus Ilídio, Neves José
Cardiology Department, Centro Hospitalar e Universitário do Algarve, Faro, Portugal,
Algarve Biomedical Center, Faro, Portugal,
Cardiology. 2019;143(3-4):116-120. doi: 10.1159/000501361. Epub 2019 Aug 30.
Direct oral anticoagulants are not approved for use in patients with mechanical valves. When used to replace vitamin K antagonists, they may cause catastrophic consequences. The authors describe the case of a patient who, after discontinuation of warfarin and introduction of rivaroxaban, developed thrombosis of his mechanical mitral prosthesis.
直接口服抗凝剂未被批准用于机械瓣膜患者。当用于替代维生素K拮抗剂时，它们可能会导致灾难性后果。作者描述了一名患者的病例，该患者在停用华法林并引入利伐沙班后，其机械二尖瓣假体发生了血栓形成。
