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乌干达东部的新生儿破伤风:实施新生儿破伤风防治方案后预后改善

Neonatal tetanus in eastern Uganda: improved outcome following the implementation of a neonatal tetanus protocol.

作者信息

Burgoine Kathy, Egiru Emma, Ikiror Juliet, Acom Linda, Akol Sylivia, Olupot-Olupot Peter

机构信息

Neonatal Lead, Neonatal Unit, Mbale Regional Referral Hospital, Mbale, Uganda.

Medical Officer, Mbale Clinical Research Institute, Mbale Regional Referral Hospital, Mbale, Uganda.

出版信息

Trop Doct. 2020 Jan;50(1):57-62. doi: 10.1177/0049475519872860. Epub 2019 Aug 31.

Abstract

Neonatal tetanus remains a significant, yet avoidable, cause of neonatal death. Despite the 34,000 deaths that occur globally from neonatal tetanus every year, there has been little research into the management of neonatal tetanus. Until worldwide elimination of neonatal tetanus is achieved, the case management of this devastating illness needs to be improved. We describe an improved outcome of neonatal tetanus following the introduction of a neonatal tetanus protocol including diazepam, magnesium sulphate, bubble continuous positive airway pressure and broad-spectrum antibiotics in a low-resource setting in eastern Uganda.

摘要

新生儿破伤风仍然是新生儿死亡的一个重要但可避免的原因。尽管全球每年有34000例新生儿死于破伤风,但对新生儿破伤风治疗的研究却很少。在全球消除新生儿破伤风之前,需要改善这种毁灭性疾病的病例管理。我们描述了在乌干达东部资源匮乏地区引入包括地西泮、硫酸镁、气泡持续气道正压通气和广谱抗生素在内的新生儿破伤风治疗方案后,新生儿破伤风治疗取得的更好效果。

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