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快速通道全髋关节和膝关节置换术后存活和出院天数:16137 例患者的观察性队列研究。

Days alive and out of hospital after fast-track total hip and knee arthroplasty: an observational cohort study in 16 137 patients.

机构信息

Section for Surgical Pathophysiology, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark; Lundbeck Foundation Centre for Fast-track Hip and Knee Replacement, Copenhagen, Denmark.

Section for Surgical Pathophysiology, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark; Lundbeck Foundation Centre for Fast-track Hip and Knee Replacement, Copenhagen, Denmark.

出版信息

Br J Anaesth. 2019 Nov;123(5):671-678. doi: 10.1016/j.bja.2019.07.022. Epub 2019 Aug 29.

Abstract

BACKGROUND

Days alive and out of hospital (DAH) has been proposed as a pragmatic outcome measure of surgical quality. However, there is a lack of procedure specific data or data within an optimised fast-track protocol. Furthermore, information about influence of follow-up duration and types of complications on DAH is limited.

METHODS

Observational multicentre cohort study of patients undergoing fast-track total hip (THA) and knee arthroplasty (TKA). Prospective information on comorbidity and complete 90 days follow-up was undertaken through the Danish National Patient Register and chart review.

RESULTS

For 16 137 procedures, of which 18.6% were high-risk (≥2 preoperative risk factors), the median length of stay was 2 days (inter-quartile range [IQR], 2-3), and 30- and 90-day readmission rates were 5.7% and 8.1%, respectively. Median DAH and DAH days were 27 (26-28) and 87 (85-88) vs 28 (27-28) and 88 (87-89) (P<0.001) in high-vs low-risk patients, respectively. The fraction with DAH ≤25 at 30 days and DAH ≤85 at 90 days was increased in high-vs low-risk patients: 23.3% vs 6.8% (odds ratio [OR]=4.16; 95% confidence interval [CI], 3.73-4.65) and 26.0% vs 8.6% (OR=3.75; 95% CI, 3.38-4.16). There were relatively fewer 'surgical' complications in high- vs low-risk patients with DAH ≤25 (14.6% vs 25.8%) (OR=0.49; 95% CI, 0.37-0.65) and DAH ≤85 (16.9% vs 31.89%) (OR=0.43; 95% CI, 0.34-0.56). About 2% of patients had readmissions, but DAH was >25 and >85 at 30 and 90 days after operation, respectively.

CONCLUSION

Median DAH in fast-track THA/TKA patients is 28 at 30 days and 88 at 90 days after surgery. DAH in high-risk patients was only slightly reduced compared with low-risk patients, but they have relatively more 'medical' complications.

摘要

背景

存活天数和出院天数(DAH)已被提议作为手术质量的实用结果衡量标准。然而,目前缺乏特定于手术的信息,也缺乏在优化的快速通道方案中的信息。此外,关于 DAH 受随访时间长短和并发症类型影响的信息有限。

方法

这是一项针对接受快速通道全髋关节置换术(THA)和膝关节置换术(TKA)的患者的观察性多中心队列研究。通过丹麦全国患者登记处和病历回顾,前瞻性地记录了合并症和完整的 90 天随访信息。

结果

在 16137 例手术中,其中 18.6%为高风险(≥2 项术前危险因素),中位住院时间为 2 天(四分位距[IQR],2-3),30 天和 90 天的再入院率分别为 5.7%和 8.1%。高风险患者的中位 DAH 和 DAH 天数分别为 27(26-28)和 87(85-88),低风险患者分别为 28(27-28)和 88(87-89)(P<0.001)。高风险患者 30 天 DAH≤25 和 90 天 DAH≤85 的比例高于低风险患者:23.3%比 6.8%(比值比[OR]=4.16;95%置信区间[CI],3.73-4.65)和 26.0%比 8.6%(OR=3.75;95% CI,3.38-4.16)。DAH≤25 的高风险患者与低风险患者相比,“手术”并发症相对较少(14.6%比 25.8%)(OR=0.49;95% CI,0.37-0.65),DAH≤85 的高风险患者与低风险患者相比,“手术”并发症相对较少(16.9%比 31.89%)(OR=0.43;95% CI,0.34-0.56)。约 2%的患者需要再次入院,但手术后 30 天和 90 天的 DAH 分别超过 25 和 85。

结论

快速通道 THA/TKA 患者的中位 DAH 在术后 30 天为 28,90 天为 88。高风险患者的 DAH 仅略低于低风险患者,但他们的“医疗”并发症相对较多。

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