Department of Respiratory Medicine, Sydney Children's Hospital, Randwick, New South Wales, Australia.
School of Women's and Children's Health, Faculty of Medicine, The University of New South Wales, Randwick, New South Wales, Australia.
Pediatr Pulmonol. 2019 Dec;54(12):1921-1926. doi: 10.1002/ppul.24491. Epub 2019 Sep 1.
Children with cystic fibrosis (CF) are routinely managed in a multidisciplinary clinic at tertiary pediatric centers. However, children with bronchiectasis may not be managed in the same way. We sought to compare the management model and clinical outcomes of children with bronchiectasis with children diagnosed with CF, in a single pediatric center.
We identified patients with bronchiectasis from hospital medical records at an urban tertiary pediatric hospital and identified a sex- and age-matched CF patient at the same center to compare lung function, nutritional status, frequency of physiotherapy and respiratory physician visits, and number of microbiological samples taken for bacterial culture.
Twenty-two children with bronchiectasis were identified, mean (standard deviation [SD]) age was 11 (3) years. The most common known etiology for bronchiectasis was postinfective (6 of 22) but was unknown in 8 of 22. The cohort with bronchiectasis had poorer lung function (FEV1 mean [SD] percent predicted 78.6 [20.5] vs 94.5 [14.7], P = .005) and had less outpatient reviews by the respiratory physician (P < .001) and respiratory physiotherapist (P < .001) when compared to those with CF. Nutritional parameters did not differ between the groups. Many children (10 of 22, 45%) with bronchiectasis did not have any microbiological respiratory tract samples taken for evaluation.
Children with bronchiectasis at this institution have poorer lung function than children with CF, and are deserving of improved multidisciplinary care.
患有囊性纤维化 (CF) 的儿童通常在三级儿科中心的多学科诊所接受常规管理。然而，患有支气管扩张症的儿童可能无法采用相同的方式进行管理。我们旨在比较单一儿科中心内支气管扩张症患儿和 CF 患儿的管理模式和临床结局。
我们从一家城市三级儿科医院的医院病历中确定了支气管扩张症患者，并在同一中心确定了一名性别和年龄匹配的 CF 患者，以比较肺功能、营养状况、物理治疗和呼吸科医生就诊的频率，以及用于细菌培养的微生物样本数量。
确定了 22 例支气管扩张症患儿，平均（标准差 [SD]）年龄为 11（3）岁。支气管扩张症最常见的已知病因是感染后（22 例中的 6 例），但有 8 例病因不明。支气管扩张症组的肺功能较差（FEV1 平均 [SD] 预计百分比 78.6 [20.5] 与 94.5 [14.7]，P = .005），并且与 CF 组相比，呼吸科医生（P < .001）和呼吸物理治疗师（P < .001）的门诊就诊次数更少。营养参数在两组之间没有差异。许多（22 例中的 10 例，45%）支气管扩张症患儿没有进行任何用于评估的微生物呼吸道样本采集。
本机构的支气管扩张症患儿的肺功能比 CF 患儿差，应给予更好的多学科治疗。
