Alexander E R
Division of Sexually Transmitted Diseases, Centers for Disease Control, Atlanta, Georgia 30333.
Ann N Y Acad Sci. 1988;549:180-6. doi: 10.1111/j.1749-6632.1988.tb23970.x.
Gonorrhea prevalence in pregnant women in the United States is generally low (less than 1%), although the prevalence in certain subsets of the population remains a matter of concern. Rates of 10% have been found in some central city adolescent prenatal clinics. Rates as high as this are quite often found in developing countries. The risks of transmission to the newborn are well studied for ophthalmia neonatorum and are 30%-40%. The risks of disseminated gonococcal infection of the newborn (sepsis or arthritis) are unmeasured, but are clearly rare events. In developing countries, maternal gonorrheal infection has been linked to premature delivery, which had been previously suggested in earlier studies in the United States. There is no evidence that the increasing occurrence of penicillinase-producing Neisseria gonorrheae (PPNG) affects maternal-neonatal transmission other than to require alternative therapy.
美国孕妇淋病患病率总体较低(低于1%),不过特定人群亚组中的患病率仍令人担忧。在一些中心城市青少年产前诊所中发现患病率达10%。在发展中国家经常能发现如此高的患病率。新生儿眼炎的传播风险已有充分研究,为30%-40%。新生儿播散性淋球菌感染(败血症或关节炎)的风险尚无测量数据,但显然是罕见事件。在发展中国家,孕产妇淋病感染与早产有关,美国早期研究也曾提出过这一点。没有证据表明产青霉素酶淋病奈瑟菌(PPNG)发生率的增加会影响母婴传播,只是需要采用替代疗法。