Brandenburg Medical School Theodor Fontane, Institute of Social Medicine and Epidemiology, Hochstraße 15, Brandenburg an der Havel, 14770, Germany.
University Hospital Heidelberg, Institute of Global Health, Im Neuenheimer Feld 324, 69120, Heidelberg, Germany.
BMC Cancer. 2019 Sep 2;19(1):869. doi: 10.1186/s12885-019-6058-6.
Few studies compared cancer incidence among migrants both to their host countries and to their population of origin. We aimed to compare cancer incidence of ethnic Germans who migrated from the former Soviet Union to Germany (resettlers) to those living in Russia as well as to the German and the Russian general populations.
The cancer registry of North Rhine-Westphalia identified incident cases of stomach, colorectal, lung, breast and prostate cancer in resettlers and the general population of the administrative district of Münster (Germany) between 2004 and 2013. The Tomsk cancer registry collected the same data in ethnic Germans and the general population of the Tomsk region (Russia). We used standardised incidence rate ratios (SIRs) to compare rates of resettlers and ethnic Germans with the respective general populations.
The total number of person-years under risk was 83,289 for ethnic Germans, 8,006,775 for the population of Tomsk, 219,604 for resettlers, and 20,516,782 for the population of Münster. Incidence of the five investigated cancer types among ethnic Germans did not differ from incidence of the general population of Tomsk. Compared to the general population of Tomsk, incidence among resettlers was higher for colorectal cancer in both sexes (females: SIR 1.45 [95% CI 1.14-1.83], males: SIR 1.56 [95% CI 1.23-1.97]), breast cancer in females (SIR 1.65 [95% CI 1.40-1.95]), and prostate cancer (SIR 1.64 [95% CI 1.34-2.01]). Incidence rates of these cancer types among resettlers were more similar to rates of the general population of Münster. Incidence of stomach and lung cancer did not differ between resettlers and the general population of Tomsk.
After an average stay of 15 years, we observed that incidence of colorectal, breast and prostate cancer among resettlers converged to levels of the general population of Münster. Resettler's incidence of stomach and lung cancer, however, was comparable to incidence in their population of origin. Causes must be investigated in subsequent analytical studies.
很少有研究将移民的癌症发病率与他们的原籍国和所在国家进行比较。我们旨在比较从前苏联移居到德国的德国裔移民（重新定居者）与居住在俄罗斯的德国裔以及德国和俄罗斯一般人群的癌症发病率。
北莱茵-威斯特法伦州的癌症登记处确定了 2004 年至 2013 年间重新定居者和明斯特行政区（德国）一般人群中的胃、结直肠、肺、乳腺和前列腺癌的发病情况。托姆斯克癌症登记处收集了同一数据，包括俄罗斯托姆斯克地区的德国裔和一般人群。我们使用标准化发病率比（SIR）来比较重新定居者和德国裔与各自一般人群的发病率。
总风险人群的人数为 83289 人，其中包括德国裔、8006775 人，托姆斯克人口、219604 人，明斯特人口。在德国裔中，五种调查癌症类型的发病率与托姆斯克一般人群的发病率没有差异。与托姆斯克一般人群相比，男性和女性的结直肠癌发病率均较高（女性：SIR1.45[95%CI1.14-1.83]，男性：SIR1.56[95%CI1.23-1.97]）、女性乳腺癌（SIR1.65[95%CI1.40-1.95]）和前列腺癌（SIR1.64[95%CI1.34-2.01]）。重新定居者的这些癌症类型的发病率更接近明斯特一般人群的发病率。重新定居者的胃癌和肺癌发病率与托姆斯克一般人群没有差异。
在平均停留 15 年后，我们观察到重新定居者的结直肠癌、乳腺癌和前列腺癌发病率趋于与明斯特一般人群的水平一致。然而，重新定居者的胃癌和肺癌发病率与原籍人口的发病率相当。在后续的分析研究中必须调查原因。
