Pandey Bedraj, Xu Shi, Ding Keying
Department of Chemistry , Middle Tennessee State University , Murfreesboro , Tennessee 37132 , United States.
Molecular Biosciences Program , Middle Tennessee State University , Murfreesboro , Tennessee 37132 , United States.
Org Lett. 2019 Sep 20;21(18):7420-7423. doi: 10.1021/acs.orglett.9b02727. Epub 2019 Sep 3.
A homogeneous cobalt-catalyzed β-alkylation of secondary alcohols with primary alcohols to selectively synthesize ketones via acceptorless dehydrogenative coupling is reported for the first time. Notably, this transformation is environmentally benign and atom economical with water and hydrogen gas as the only byproducts.
首次报道了一种均相钴催化的仲醇与伯醇的β-烷基化反应，通过无受体脱氢偶联选择性合成酮。值得注意的是，这种转化对环境友好且原子经济，唯一的副产物是水和氢气。
