Institute of Qinghai-Tibetan Plateau, Southwest Minzu University, Chengdu 610041, Sichuan Province, China.
State Key Laboratories for Quality Research in Chinese Medicines, Faculty of Chinese Medicine, Macau University of Science and Technology, Macau 853, China.
Molecules. 2019 Sep 2;24(17):3188. doi: 10.3390/molecules24173188.
is a herb used in traditional Chinese medicine, where it is known as . Its bioactive qualities are influenced by the post-harvest processing methods used (such as drying). However, changes in chemical components according to the drying method are unknown. Fresh roots and rhizomes of were subjected to seven drying methods. Chromatography-mass spectrometry combined with targeted and untargeted analyses were used to investigate relationships between drying methods and chemical concentrations. According to targeted evaluations of the six main bioactive constituents, their total contents decreased significantly in all drying methods. Hierarchical clustering analysis of the drying methods and total metabolome detected 30 chemical constituents, for which heap maps were obtained. Hot air drying was the best processing method, producing the least chemical changes at the lowest cost, while shade drying caused the greatest chemical changes. In conclusion, the wide range of chemical changes in caused by drying was investigated. Such changes potentially affect the quality of herbal medicines.
是一种在传统中药中使用的草药，在中文中被称为 。其生物活性品质受收获后加工方法（如干燥）的影响。然而，根据干燥方法的化学成分变化尚不清楚。将 的新鲜根和根茎进行了七种干燥方法处理。采用色谱-质谱联用技术结合靶向和非靶向分析，研究了干燥方法与化学浓度之间的关系。根据对六种主要生物活性成分的靶向评价，它们在所有干燥方法中的总含量都显著降低。对干燥方法和总代谢组的层次聚类分析检测到 30 种化学成分，并获得了它们的堆积图。热空气干燥是最佳的加工方法，以最低的成本产生最小的化学变化，而阴凉处干燥则会引起最大的化学变化。总之，研究了 因干燥而产生的广泛的化学变化。这些变化可能会影响草药的质量。
