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HPLC-DAD-MS 法同时测定不同商品部位独活中化学成分的含量

Quantitative analysis of chemical constituents in different commercial parts of Notopterygium incisum by HPLC-DAD-MS.

机构信息

Chengdu Institute of Biology, Chinese Academy of Sciences, Chengdu 610041, PR China.

出版信息

J Ethnopharmacol. 2009 Dec 10;126(3):474-9. doi: 10.1016/j.jep.2009.09.011. Epub 2009 Sep 23.

DOI:10.1016/j.jep.2009.09.011
PMID:19781618
Abstract

ETHNOPHARMACOLOGICAL RELEVANCE

Notopterygium incisum used as an antirheumatic and analgesic medicine for the treatment of rheumatism, headache, cold, etc., is not only a traditional Qiang medicine, but also a traditional Tibetan remedy for thousands of years.

AIM OF THE STUDY

In order to use this herbal medicine in a more effective way, in the present investigation, we analyzed the main chemical constituents of different commercial parts as well as fibrous roots of Notopterygium incisum.

MATERIALS AND METHODS

All crude Notopterygium incisum samples used in this study were collected in Sichuan province of China. We used HPLC-DAD-MS to analyze quantitatively the main chemical constituents of different commercial parts as well as fibrous roots of Notopterygium incisum.

RESULTS

According to different commercial parts, 10 Notopterygium incisum samples collected from two main production areas have been investigated, and four main constituents have been quantitatively analyzed.

CONCLUSION

The quality of rhizomes is better than that of main roots. Unexpectedly, the content of two main constituents, notopterol and isoimperaorin, in fibrous roots is higher than any other parts of Notopterygium incisum. This result implied that the fibrous root may also have value, and we should study it to explore its potential.

摘要

民族药理学相关性

羌活作为一种治疗风湿、头痛、感冒等疾病的抗风湿和镇痛药,不仅是一种传统的羌药,也是千百年来藏医的传统疗法。

研究目的

为了更有效地使用这种草药,在本研究中,我们分析了不同商品部位以及羌活纤维根的主要化学成分。

材料和方法

本研究中使用的所有羌活粗提物样品均采自中国四川省。我们使用 HPLC-DAD-MS 对不同商品部位以及羌活纤维根的主要化学成分进行定量分析。

结果

根据不同的商品部位,我们从两个主要产区采集了 10 个羌活样品,并对其中的 4 种主要成分进行了定量分析。

结论

根状茎的质量优于主根。出乎意料的是,纤维根中两种主要成分羌活醇和异欧前胡素的含量高于羌活的任何其他部位。这一结果表明,纤维根可能也有价值,我们应该对其进行研究,以探索其潜力。

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