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疼痛耐受性的早期变化可预测慢性疼痛跨学科治疗的疼痛结局。

Early Changes in Pain Acceptance Predict Pain Outcomes in Interdisciplinary Treatment for Chronic Pain.

作者信息

Probst Thomas, Jank Robert, Dreyer Nele, Seel Stefanie, Wagner Ruth, Hanshans Klaus, Reyersbach Renate, Mühlberger Andreas, Lahmann Claas, Pieh Christoph

机构信息

Department for Psychotherapy and Biopsychosocial Health, Danube University Krems, 3500 Krems, Austria.

Institute for Psychology, Regensburg University, 93053 Regensburg, Germany.

出版信息

J Clin Med. 2019 Sep 2;8(9):1373. doi: 10.3390/jcm8091373.

Abstract

Studies have shown that pain acceptance is associated with a better pain outcome. The current study explored whether changes in pain acceptance in the very early treatment phase of an interdisciplinary cognitive-behavioral therapy (CBT)-based treatment program for chronic pain predict pain outcomes. A total of 69 patients with chronic, non-malignant pain (at least 6 months) were treated in a day-clinic for four-weeks. Pain acceptance was measured with the Chronic Pain Acceptance Questionnaire (CPAQ), pain outcomes included pain intensity (Numeric Rating Scale, NRS) as well as affective and sensory pain perception (Pain Perception Scale, SES-A and SES-S). Regression analyses controlling for the pre-treatment values of the pain outcomes, age, and gender were performed. Early changes in pain acceptance predicted pain intensity at post-treatment measured with the NRS (B = -0.04 (SE = 0.02); T = -2.28; = 0.026), affective pain perception at post-treatment assessed with the SES-A (B = -0.26 (SE = 0.10); T = -2.79; = 0.007), and sensory pain perception at post-treatment measured with the SES-S (B = -0.19 (SE = 0.08); T = -2.44; = 0.017) . Yet, a binary logistic regression analysis revealed that early changes in pain acceptance did not predict clinically relevant pre-post changes in pain intensity (at least 2 points on the NRS). Early changes in pain acceptance were associated with pain outcomes, however, the impact was beneath the threshold defined as clinically relevant.

摘要

研究表明,疼痛接纳与更好的疼痛结局相关。本研究探讨了在基于跨学科认知行为疗法(CBT)的慢性疼痛治疗项目的极早期治疗阶段,疼痛接纳的变化是否能预测疼痛结局。共有69例慢性非恶性疼痛(至少6个月)患者在日间诊所接受了为期四周的治疗。采用慢性疼痛接纳问卷(CPAQ)测量疼痛接纳情况,疼痛结局包括疼痛强度(数字评定量表,NRS)以及情感性和感觉性疼痛感知(疼痛感知量表,SES-A和SES-S)。进行了回归分析,控制了疼痛结局、年龄和性别的治疗前值。疼痛接纳的早期变化预测了治疗后用NRS测量的疼痛强度(B = -0.04(标准误 = 0.02);T = -2.28;P = 0.026),治疗后用SES-A评估的情感性疼痛感知(B = -0.26(标准误 = 0.10);T = -2.79;P = 0.007),以及治疗后用SES-S测量的感觉性疼痛感知(B = -0.19(标准误 = 0.08);T = -2.44;P = 0.017)。然而,二元逻辑回归分析显示,疼痛接纳的早期变化并不能预测疼痛强度临床上相关的治疗前后变化(NRS上至少2分)。疼痛接纳的早期变化与疼痛结局相关,然而,其影响低于定义为临床相关的阈值。

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