Institute of Population Health, University of Liverpool, Liverpool L69 3BX, UK
J Med Ethics. 2020 Mar;46(3):220-222. doi: 10.1136/medethics-2019-105629. Epub 2019 Sep 3.
In their paper Horton argue that it is acceptable to contact an anonymous egg-donor to facilitate diagnostic genetic testing for the donor conceived child, despite the donor, 'indicating on a historical consent form that she did not wish to take part in future research, and that she did not wish to be informed if she was found to be a carrier of a "harmful inherited condition"'. There are a number of claims embedded in Horton 's position that it is acceptable to contact the donor and request that she at least think about participating in genetic testing. In this response. I will go through their main claims and argue that the area of genomic medicine does not justify exceptions to general consent conditions as the authors suppose and conclude that the donor should not be contacted. I will then go on to suggest a policy change that would address Horton 's concerns but would not involve over-riding any previously expressed wishes.
在他们的论文中， Horton 等人认为，尽管捐卵者在历史同意书中表示她不愿意参与未来的研究，也不愿意在发现她是“有害遗传疾病”携带者时被通知，但为了方便对捐卵受孕孩子进行诊断性基因检测，可以联系匿名捐卵者，这种做法是可以接受的。 Horton 的立场中包含了一些主张，即联系捐卵者并要求她至少考虑参与基因检测是可以接受的。在本回应中，我将详细阐述他们的主要主张，并论证基因组医学领域并不能为作者所假设的一般同意条件的例外情况提供依据，并得出结论，即不应联系捐卵者。然后，我将提出一项政策变更建议，以解决 Horton 的担忧，但不会违背之前的任何意愿表达。
