Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, New York; and
Department of Nuclear Medicine, Baden Cantonal Hospital, Baden, Switzerland.
J Nucl Med. 2019 Oct;60(10):1350-1358. doi: 10.2967/jnumed.119.228320. Epub 2019 Sep 3.
Prostate cancer is a very heterogeneous disease, and contemporary management is focused on identification and treatment of the prognostically adverse high-risk tumors while minimizing overtreatment of indolent, low-risk tumors. In recent years, imaging has gained increasing importance in the detection, staging, posttreatment assessment, and detection of recurrence of prostate cancer. Several imaging modalities including conventional and functional methods are used in different clinical scenarios with their very own advantages and limitations. This continuing medical education article provides an overview of available imaging modalities currently in use for prostate cancer followed by a more specific section on the value of these different imaging modalities in distinct clinical scenarios, ranging from initial diagnosis to advanced, metastatic castration-resistant prostate cancer. In addition to established imaging indications, we will highlight some potential future applications of contemporary imaging modalities in prostate cancer.
前列腺癌是一种非常异质性的疾病,当代的治疗方法主要集中在识别和治疗预后不良的高危肿瘤,同时最大限度地减少对惰性、低风险肿瘤的过度治疗。近年来,影像学在前列腺癌的检测、分期、治疗后评估和复发检测方面的重要性日益增加。几种影像学方法,包括传统和功能方法,在不同的临床情况下使用,各有其优点和局限性。这篇继续医学教育文章概述了目前用于前列腺癌的影像学方法,然后更具体地介绍了这些不同影像学方法在不同临床情况下的价值,从初始诊断到晚期、转移性去势抵抗性前列腺癌。除了已确立的影像学适应证外,我们还将强调当代影像学方法在前列腺癌中的一些潜在的未来应用。