Diabetes association of polyps and colon cancer.

AIM

The aim of the study was to retrospectively assess the relationship between the occurrence of polyps and colon cancer in patients with type 2 diabetes.

METHODS

In 2014-2015, 976 colonoscopies were performed in patients. We compared the number of polyps with high-grade dysplasia and colorectal cancers in patients with and without diabetes. In addition, in the diabetic group we documented the relationship between HbA1C and the occurrence of polyps with high-grade dysplasia, and colon cancer. The data were statistically analyzed.

RESULTS

1. Patients with diabetes show a higher incidence of polyps with high-grade dysplasia/carcinoma - 32/91 (35.16%) in comparison to patients without diabetes - 136/885 (15.37%), P < 0.001; 2. Patients with diabetes show a higher incience of polyps with cancer - 9/91 (9.89%) as compared to patients without diabetes - 18/885 (2.03%), P < 0.001. 3) Colorectal cancer occurred significantly more often in uncontrolled diabetes (P = 0.022).

CONCLUSION

The conducted study shows a significant association between type 2 diabetes and the incidence of colorectal adenomas. These findings may lead to a conclusion that diabetic patients are at a higher risk of developing colorectal cancer, thus are in higher need for controlled colonoscopy. Therefore, it may be worth considering a scheme for screening patients in the above-mentioned group with colonoscopy.