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尼日利亚成年2型糖尿病患者的全球残疾负担及其预测因素。

Global disability burden and its predictors among adult Nigerians living with Type-2 diabetes.

作者信息

Oyewole Olufemi O, Odusan Olatunde, Ale Ayotunde O

机构信息

Physiotherapy Department, Olabisi Onabanjo University Teaching Hospital, Nigeria.

Medicine Department, Olabisi Onabanjo University Teaching Hospital, Nigeria.

出版信息

Ghana Med J. 2019 Jun;53(2):135-141. doi: 10.4314/gmj.v53i2.8.

Abstract

BACKGROUND

Type 2 diabetes mellitus (T2DM) is a public health issue associated with a high prevalence of disability. Studies on disability profile in terms of reduction in body structure and function, personal activities and societal participation, defined as 'global disability', are scarce among people living with T2DM in Nigeria.

OBJECTIVES

To assess the prevalence of global disability and its predictors among Nigerian living with T2DM.

METHODS

A cross-sectional analysis of 162 patients diagnosed with T2DM and attending a tertiary health facility was performed for global disability measure and function. Their clinical and socio-demographic data were obtained. Poisson regression analysis was applied to assess the predicting factors of disability.

RESULTS

A mean global disability score of 22.1 was reported among the participants, varying from moderate to high in each item. About 25.0% had mild disability, while 60.5% reported moderate to severe disability. Elevated glycosylated haemoglobin, fasting blood glucose, systolic blood pressure, age, disease duration and marital status predicted disability. A unit increase in HbA1c, systolic blood pressure and 1 month increase in DM duration had more disability reported estimates [1.062 (CI=1.050-1.075), 1.005 (CI=1.002-1.007) and 1.001 (CI=1.000-1.002) times, respectively]. Married participants were 1.13 (CI=1.02-1.23) times more likely to be disabled than unmarried.

CONCLUSIONS

There is mild to moderate burden and risk of global disability among Nigerian living with T2DM. Age, DM duration, marital status, fasting blood glucose, glycosylated haemoglobin and systolic hypertension significantly predicted disability.

FUNDING

None declared.

摘要

背景

2型糖尿病(T2DM)是一个与高致残率相关的公共卫生问题。在尼日利亚的2型糖尿病患者中,关于从身体结构和功能、个人活动及社会参与方面的减少来定义的“整体残疾”情况的研究很少。

目的

评估尼日利亚2型糖尿病患者中整体残疾的患病率及其预测因素。

方法

对162名诊断为2型糖尿病并在一家三级医疗机构就诊的患者进行横断面分析,以测量整体残疾情况和功能。获取了他们的临床和社会人口统计学数据。应用泊松回归分析来评估残疾的预测因素。

结果

参与者的平均整体残疾评分为22.1,各项评分从中度到高度不等。约25.0%的人有轻度残疾,而60.5%的人报告有中度至重度残疾。糖化血红蛋白、空腹血糖、收缩压升高、年龄、病程和婚姻状况可预测残疾情况。糖化血红蛋白、收缩压每升高一个单位以及糖尿病病程每增加1个月,报告的残疾估计值增加更多[分别为1.062(CI = 1.050 - 1.075)、1.005(CI = 1.002 - 1.007)和1.001(CI = 1.000 - 1.002)倍]。已婚参与者残疾的可能性比未婚者高1.13(CI = 1.02 - 1.23)倍。

结论

尼日利亚的2型糖尿病患者存在轻度至中度的整体残疾负担和风险。年龄、糖尿病病程、婚姻状况、空腹血糖、糖化血红蛋白和收缩期高血压是残疾的显著预测因素。

资金来源

未声明。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d69b/6697762/2592d75db8bb/GMJ5302-0135Fig1.jpg

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