Comparison of chest X-ray lesion characteristics of multidrug-resistant tuberculosis and non-tuberculous mycobacterial infection.

PURPOSE

This research aimed to compared chest radiographic characteristics of multidrug-resistant tuberculosis (MDR-TB) and non-tuberculous mycobacteria (NTM) infection, which can be used in early diagnostic screening.

MATERIAL AND METHODS

The method of this study was cross-sectional to obtain the relationship between radiographic findings.

RESULTS

Among 538 subjects who were positive for TB during screening, 11 (2.04%) had MDR-TB, 147 (27.32%) had drug-sensitive TB, and 380 (70.63%) had NTM infection. The radiographic findings that correlated with MDR-TB were infiltrates ( = 0.010), cavities ( = 0.021), nodules ( = 0.001), and fibrosis ( = 0.010), with the best predictor of MDR-TB lesions being the presence of a nodule. The lesion locations related to MDR-TB were the upper right and left lung ( = 0.00). There were no specific lesions present in NTM infection ( < 0.05) because almost all had a meaningful correlation ( < 0.05), except the presence of a mass. The lesion location related to NTM infection was the medial aspect of the left lung ( = 0.01), and the lesion extent was also correlated ( < 0.05).

CONCLUSIONS

Chest X-ray lesion characteristics of MDR-TB show significant correlation among cavities, nodules, and fibrosis. There were no specific lesions that could differentiate NTM infection from MDR-TB; however, the most common lesion location in NTM infection was the medial aspect of the left lung.