Majdawati Ana, Icksan Aziza Ghanie, Lolong Dina
Department of Radiology, Faculty of Medicine Health Sciences, Universitas Muhammadiyah Yogyakarta, Indonesia.
Department of Radiology Persahabatan Hospital Jakarta, East Jakarta, Jakarta, Indonesia.
Pol J Radiol. 2019 Mar 23;84:e162-e170. doi: 10.5114/pjr.2019.84515. eCollection 2019.
This research aimed to compared chest radiographic characteristics of multidrug-resistant tuberculosis (MDR-TB) and non-tuberculous mycobacteria (NTM) infection, which can be used in early diagnostic screening.
The method of this study was cross-sectional to obtain the relationship between radiographic findings.
Among 538 subjects who were positive for TB during screening, 11 (2.04%) had MDR-TB, 147 (27.32%) had drug-sensitive TB, and 380 (70.63%) had NTM infection. The radiographic findings that correlated with MDR-TB were infiltrates ( = 0.010), cavities ( = 0.021), nodules ( = 0.001), and fibrosis ( = 0.010), with the best predictor of MDR-TB lesions being the presence of a nodule. The lesion locations related to MDR-TB were the upper right and left lung ( = 0.00). There were no specific lesions present in NTM infection ( < 0.05) because almost all had a meaningful correlation ( < 0.05), except the presence of a mass. The lesion location related to NTM infection was the medial aspect of the left lung ( = 0.01), and the lesion extent was also correlated ( < 0.05).
Chest X-ray lesion characteristics of MDR-TB show significant correlation among cavities, nodules, and fibrosis. There were no specific lesions that could differentiate NTM infection from MDR-TB; however, the most common lesion location in NTM infection was the medial aspect of the left lung.
本研究旨在比较耐多药结核病（MDR-TB）和非结核分枝杆菌（NTM）感染的胸部X线特征，以便用于早期诊断筛查。
本研究采用横断面研究方法来获取影像学表现之间的关系。
在筛查中结核呈阳性的538名受试者中，11例（2.04%）为耐多药结核病，147例（27.32%）为药物敏感结核病，380例（70.63%）为非结核分枝杆菌感染。与耐多药结核病相关的影像学表现为浸润（P = 0.010）、空洞（P = 0.021）、结节（P = 0.001）和纤维化（P = 0.010），耐多药结核病变的最佳预测指标是结节的存在。与耐多药结核病相关的病变部位是右上肺和左上肺（P = 0.00）。非结核分枝杆菌感染中没有特异性病变（P < 0.05），因为几乎所有病变都有显著相关性（P < 0.05），除了肿块的存在。与非结核分枝杆菌感染相关的病变部位是左肺内侧（P = 0.01），病变范围也具有相关性（P < 0.05）。
耐多药结核病的胸部X线病变特征在空洞、结节和纤维化之间显示出显著相关性。没有可区分非结核分枝杆菌感染和耐多药结核病的特异性病变；然而，非结核分枝杆菌感染最常见的病变部位是左肺内侧。
