Icksan Aziza Ghanie, Napitupulu Martin Raja Sonang, Nawas Mohamad Arifin, Nurwidya Fariz
Department of Radiology, Persahabatan Hospital, Jakarta, Indonesia.
Department of Pulmonology and Respiratory Medicine, Persahabatan Hospital, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia.
J Nat Sci Biol Med. 2018 Jan-Jun;9(1):42-46. doi: 10.4103/jnsbm.JNSBM_79_17.
Imaging has a big role in tuberculosis (TB) diagnosis and chest X-ray is preferable because it is available in primary health care and can point out the location, area, and morphology of lesions, such as cavity, consolidation, pleural effusions, and fibrosis. We aimed to compare the chest X-ray findings in multi-drug resistant TB (MDR-TB) and in drug-sensitive TB (DS-TB) cases.
This is a retrospective cross-sectional study which compares chest X-ray findings of two groups of patients, involving 183 DS-TB patients and 183 MDR-TB patients. Radiologic findings that we analyzed were infiltrate, consolidation, cavity, ground glass opacity, fibrosis, bronchiectasis, calcification, node, atelectasis, bullae, emphysema, and other nonlung parenchymal findings.
MDR-TB group have 177 (96%) patients with large lesions, 6 (4%) with medium lesions, and no small lesions. DS-TB group have 55 (30%) patients with small lesions, 78 (43%) with medium lesions, and 50 (27%) with large lesions. Active TB lesions in the forms of infiltrate and ground-glass opacity were more dominant in DS-TB group, whereas consolidation, cavity, fibrosis, bronchiectasis, calcification, node, atelectasis, bullae, emphysema, and other nonlung parenchymal findings, were more dominant in MDR-TB.
There were significant differences in chest X-ray findings between MDR-TB and DS-TB in terms of lesion size and morphology. Recognition of chest X-ray findings could help the physician to differentiate patient with suspected MDR-TB.
影像学在结核病(TB)诊断中发挥着重要作用,胸部X线检查更为可取,因为它在初级卫生保健中即可进行,并且能够指出病变的位置、范围和形态,如空洞、实变、胸腔积液和纤维化。我们旨在比较耐多药结核病(MDR-TB)和药物敏感结核病(DS-TB)病例的胸部X线检查结果。
这是一项回顾性横断面研究,比较两组患者的胸部X线检查结果,其中包括183例DS-TB患者和183例MDR-TB患者。我们分析的放射学表现包括浸润、实变、空洞、磨玻璃影、纤维化、支气管扩张、钙化、结节、肺不张、肺大疱、肺气肿以及其他非肺实质表现。
MDR-TB组有177例(96%)患者有大病灶,6例(4%)有中等病灶,无小病灶。DS-TB组有55例(30%)患者有小病灶,78例(43%)有中等病灶,50例(27%)有大病灶。DS-TB组以浸润和磨玻璃影形式存在的活动性结核病灶更为常见,而实变、空洞、纤维化、支气管扩张、钙化、结节、肺不张、肺大疱、肺气肿以及其他非肺实质表现,在MDR-TB组更为常见。
MDR-TB和DS-TB在胸部X线检查结果的病灶大小和形态方面存在显著差异。认识胸部X线检查结果有助于医生鉴别疑似MDR-TB患者。