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视觉模拟评分法可检测哮喘患儿运动诱发的支气管收缩。

The Visual Analog Scale detects exercise-induced bronchoconstriction in children with asthma.

机构信息

Department of Pediatrics, Medisch Spectrum Twente, Enschede, the Netherlands.

Roessingh Research and Development, Enschede, the Netherlands.

出版信息

J Asthma. 2020 Dec;57(12):1347-1353. doi: 10.1080/02770903.2019.1652640. Epub 2019 Sep 4.

Abstract

Exercise-induced bronchoconstriction (EIB) is a specific morbidity of childhood asthma and an important sign of uncontrolled asthma. The occurrence of EIB is insufficiently identified by the Childhood Asthma Control Test (C-ACT) and Asthma Control Test (ACT). This study aimed to (1) evaluate the Visual Analog Scale (VAS) for dyspnea as a tool to detect EIB in asthmatic children and (2) assess the value of combining (C-)ACT outcomes with VAS scores. We measured EIB in 75 asthmatic children (mean age 10.8 years) with a standardized exercise challenge test (ECT) performed in cold and dry air. Children and parents reported VAS dyspnea scores before and after the ECT. Asthma control was assessed by the (C-)ACT. Changes in VAS scores (ΔVAS) of children and parents correlated moderately with fall in forced expiratory volume in 1 second (FEV), respectively =0.57 ( < .001) and =0.58 ( < .001). At a ΔVAS cutoff value of ≥3 in children, sensitivity and specificity for EIB were 80% and 79% (AUC 0.82). Out of 38 children diagnosed with EIB, 37 had a (C-)ACT score of ≤19 and/or a ΔVAS of ≥3, corresponding with a sensitivity of 97% and a negative predictive value of 96%. This study shows that the VAS could be an effective additional tool for diagnosing EIB in children. A reported difference in VAS scores of ≥3 after a standardized ECT combined with low (C-)ACT scores was highly effective in detecting and excluding EIB.

摘要

运动诱发性支气管收缩(EIB)是儿童哮喘的一种特定疾病,也是哮喘未得到控制的一个重要标志。通过儿童哮喘控制测试(C-ACT)和哮喘控制测试(ACT)对 EIB 的识别不够充分。本研究旨在:(1)评估呼吸困难视觉模拟量表(VAS)作为检测哮喘儿童 EIB 的工具;(2)评估将(C-)ACT 结果与 VAS 评分相结合的价值。我们对 75 名哮喘儿童(平均年龄 10.8 岁)进行了标准化运动挑战测试(ECT),在寒冷干燥的空气中进行。儿童和家长在 ECT 前后报告了 VAS 呼吸困难评分。哮喘控制通过(C-)ACT 进行评估。儿童和家长的 VAS 评分变化(ΔVAS)与用力呼气量(FEV)的下降分别中度相关,相关系数分别为 =0.57( < .001)和 =0.58( < .001)。在儿童的 ΔVAS 截值≥3 时,EIB 的敏感性和特异性分别为 80%和 79%(AUC 0.82)。在诊断为 EIB 的 38 名儿童中,有 37 名儿童的(C-)ACT 评分≤19 且/或 ΔVAS≥3,其敏感性为 97%,阴性预测值为 96%。本研究表明,VAS 可能是诊断儿童 EIB 的一种有效附加工具。报告的 ECT 后 VAS 评分差异≥3 与低(C-)ACT 评分相结合,可高度有效地检测和排除 EIB。

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