2000-2003 年韩国发生的严重发热伴血小板减少综合征病毒感染或与丛林斑疹伤寒混合感染。
Severe Fever with Thrombocytopenia Syndrome Virus Infection or Mixed Infection with Scrub Typhus in South Korea in 2000-2003.
机构信息
Department of Microbiology and Immunology, Seoul National University College of Medicine, Seoul, South Korea.
Department of Biomedical Sciences, Seoul National University College of Medicine, Seoul, South Korea.
出版信息
Am J Trop Med Hyg. 2019 Nov;101(5):1096-1099. doi: 10.4269/ajtmh.19-0392.
Severe fever with thrombocytopenia syndrome is a tick-borne viral disease, with a high mortality rate that was first reported in China in 2009. Scrub typhus is an acute febrile illness caused by , a bacterium transmitted to humans through chigger mite bites. Severe fever with thrombocytopenia syndrome and scrub typhus are endemic to South Korea. To investigate evidence of severe fever with thrombocytopenia syndrome virus (SFTSV) infection or mixed infection with scrub typhus in South Korea, we examined 2,329 sera samples collected from patients presenting from November 1, 2000, to November 1, 2003, for the diagnosis of rickettisal diseases at Seoul National University, Seoul, South Korea. We found retrospective evidence of SFTSV infection or mixed infection with scrub typhus in South Korea in 2000-2003. Severe fever with thrombocytopenia syndrome virus infections in South Korea occurred before previously reported cases and were more concurrent with those in China. It is important to consider SFTSV infection in patients with scrub typhus.
严重发热伴血小板减少综合征是一种蜱传病毒性疾病，死亡率高，于 2009 年在中国首次报告。恙虫病是一种由恙虫病东方体引起的急性发热性疾病，通过恙螨幼虫叮咬传播给人类。严重发热伴血小板减少综合征和恙虫病在韩国流行。为了调查韩国严重发热伴血小板减少综合征病毒（SFTSV）感染或与恙虫病混合感染的证据，我们检查了 2329 份血清样本，这些样本是 2000 年 11 月 1 日至 2003 年 11 月 1 日期间在韩国首尔国立大学为诊断立克次体病而采集的。我们发现了韩国在 2000-2003 年有 SFTSV 感染或与恙虫病混合感染的回顾性证据。韩国的严重发热伴血小板减少综合征病毒感染发生在之前报告的病例之前，与中国的病例更为同时发生。在患有恙虫病的患者中，需要考虑 SFTSV 感染的可能性。
Zotero 插件