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用于逆转直接口服抗凝剂的andexanet alfa(Andexxa)。

Andexanet Alfa (Andexxa) for the Reversal of Direct Oral Anticoagulants.

作者信息

Momin Jayed H, Candidate PharmD, Hughes Gregory J

出版信息

P T. 2019 Sep;44(9):530-549.

Abstract

Andexanet alfa (Andexxa) for the reversal of direct oral anticoagulants.

摘要

用于逆转直接口服抗凝剂的andexanet alfa(Andexxa)。

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本文引用的文献

1
Full Study Report of Andexanet Alfa for Bleeding Associated with Factor Xa Inhibitors.
N Engl J Med. 2019 Apr 4;380(14):1326-1335. doi: 10.1056/NEJMoa1814051. Epub 2019 Feb 7.
2
Andexanet Alfa: First Global Approval.
Drugs. 2018 Jul;78(10):1049-1055. doi: 10.1007/s40265-018-0940-4.
3
Safety, pharmacokinetics, and reversal of apixaban anticoagulation with andexanet alfa.
Blood Adv. 2017 Sep 22;1(21):1827-1838. doi: 10.1182/bloodadvances.2017007112. eCollection 2017 Sep 26.
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Evaluation of bleeding in patients receiving direct oral anticoagulants.
Vasc Health Risk Manag. 2017 Aug 23;13:325-342. doi: 10.2147/VHRM.S121661. eCollection 2017.
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Andexanet Alfa for the Reversal of Factor Xa Inhibitor Activity.
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National Trends in Ambulatory Oral Anticoagulant Use.
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The real decoy: an antidote for factor Xa-directed anticoagulants.
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