Motor Control Research Lab, Department of Kinesiology and Community Health, University of Illinois Urbana-Champaign, 301 Freer Hall 906 S Goodwin Ave, Urbana, IL, 61801, USA.
M-Sense Research Group, Department of Electrical and Biomedical Engineering, University of Vermont, Burlington, VT, 05405, USA.
Curr Neurol Neurosci Rep. 2019 Sep 4;19(10):80. doi: 10.1007/s11910-019-0997-9.
Walking impairments are highly prevalent in persons with multiple sclerosis (PwMS) and are associated with reduced quality of life. Walking is traditionally quantified with various measures, including patient self-reports, clinical rating scales, performance measures, and advanced lab-based movement analysis techniques. Yet, the majority of these measures do not fully characterize walking (i.e., gait quality) nor adequately reflect walking in the real world (i.e., community ambulation) and have limited timescale (only measure walking at a single point in time). We discuss the potential of wearable sensors to provide sensitive, objective, and easy-to-use assessment of community ambulation in PwMS.
Wearable technology has the ability to measure all aspects of gait in PwMS yet is under-studied in comparison with other populations (e.g., older adults). Within the studies focusing on PwMS, half that measure pace collected free-living data, while only one study explored gait variability in free-living conditions. No studies explore gait asymmetry or complexity in free-living conditions. Wearable technology has the ability to provide objective, comprehensive, and sensitive measures of gait in PwMS. Future research should investigate this technology's ability to accurately assess free-living measures of gait quality, specifically gait asymmetry and complexity.
多发性硬化症患者(PwMS)普遍存在行走障碍,这与生活质量下降有关。行走传统上通过各种方法进行量化,包括患者自我报告、临床评估量表、表现测量以及先进的实验室运动分析技术。然而,这些方法中的大多数都不能完全描述行走(即步态质量),也不能充分反映现实世界中的行走(即社区行走),并且时间尺度有限(仅在单一时间点测量行走)。我们讨论了可穿戴传感器在提供 PwMS 社区行走敏感、客观和易用评估方面的潜力。
与其他人群(例如老年人)相比,可穿戴技术具有测量 PwMS 步态各个方面的能力,但研究较少。在专门针对 PwMS 的研究中,有一半的测量步速的研究收集了自由生活数据,而只有一项研究探索了自由生活条件下的步态变异性。没有研究在自由生活条件下探索步态不对称或复杂性。可穿戴技术具有提供 PwMS 步态客观、全面和敏感测量的能力。未来的研究应调查该技术在准确评估步态质量的自由生活测量方面的能力,特别是步态不对称性和复杂性。