Saul Dominik, Seitz Mark-Tilmann, Weiser Lukas, Oberthür Swantje, Roch Jonathan, Bremmer Felix, Perske Christina, Viezens Lennart, Sehmisch Stephan, Lehmann Wolfgang
Department of Trauma, Orthopedics and Reconstructive Surgery, Georg-August-University of Göttingen, Göttingen, Germany.
Institute of Pathology, University Medical Center Göttingen, Georg-August-University of Göttingen, Göttingen, Germany.
J Neurol Surg A Cent Eur Neurosurg. 2020 Jan;81(1):86-90. doi: 10.1055/s-0039-1693707. Epub 2019 Sep 4.
The cestode causes hydatid disease. In addition to manifestations in the liver and lung, it can lead to cystic lesions in the spine.
We report a 42-year-old male patient with primary hydatid disease in the eighth thoracic vertebra. The only clinical symptom was chronic back pain. Although laboratory findings were normal, imaging displayed lytic destruction that raised the suspicion of a metastatic disease. Diagnostics of the thoraces and abdomen did not reveal other pathologic abnormalities. Follow-up magnetic resonance imaging (MRI) depicted a progressive compression of the spinal cord and inhomogeneous structure in the fat-suppressed sequences. Because the Jamshidi biopsy was inconclusive, the tumor board recommended surgery. Dorsal decompression, spondylodesis of T6-T10, and vertebral column resection of T8 with complete cyst removal were performed. The resected vertebrae showed a mucous-like lesion with white granular tissue interfusing the whole vertebral body. A pathologic examination and enzyme-linked immunosorbent assay confirmed . Thus chemotherapy with albendazole was initiated. A follow-up MRI of the whole spine confirmed complete remission and found no additional resettlements. The patient's back pain was resolved without neurologic deficits.
For lytic manifestations of the vertebral column, hydatid cysts should be considered a differential diagnosis in addition to malignant metastasis, tuberculosis, and osteomyelitis. Thorough surgical resection and strict follow-up are necessary.
该绦虫可引发包虫病。除了在肝脏和肺部出现症状外,它还可导致脊柱出现囊性病变。
我们报告一名42岁男性患者,第八胸椎患有原发性包虫病。唯一的临床症状是慢性背痛。尽管实验室检查结果正常,但影像学显示溶骨性破坏,这引发了对转移性疾病的怀疑。胸部和腹部检查未发现其他病理异常。后续的磁共振成像(MRI)显示脊髓逐渐受压,脂肪抑制序列中结构不均匀。由于Jamshidi活检结果不明确,肿瘤委员会建议进行手术。实施了后路减压、T6 - T10椎体融合术以及T8椎体切除术并完整切除囊肿。切除的椎体显示出类似黏液的病变,白色颗粒组织贯穿整个椎体。病理检查和酶联免疫吸附测定得以确诊。因此开始使用阿苯达唑进行化疗。全脊柱的后续MRI证实完全缓解,未发现其他再发情况。患者的背痛得以缓解,无神经功能缺损。
对于脊柱的溶骨性表现,除了恶性转移、结核和骨髓炎外,包虫囊肿应被视为鉴别诊断之一。彻底的手术切除和严格的随访是必要的。