Division of Cardiac Rehabilitation, Department of Physical Medicine & Rehabilitation, Xiangya Hospital Central South University, Changsha, Hunan, People's Republic of China; Division of Preventive Cardiology, Department of Cardiovascular Medicine, Mayo Clinic, Rochester, MN.
Division of Preventive Cardiology, Department of Cardiovascular Medicine, Mayo Clinic, Rochester, MN.
Mayo Clin Proc. 2019 Sep;94(9):1718-1730. doi: 10.1016/j.mayocp.2019.04.033.
To examine the effect of high-intensity interval training (HIIT) on body fat mass and distribution in patients with myocardial infarction (MI) who underwent cardiac rehabilitation (CR).
We retrospectively screened 391 consecutive patients with MI enrolled in CR between September 1, 2015, and February 28, 2018. We included 120 patients who completed 36 CR sessions and underwent pretest-posttest dual-energy x-ray absorptiometry; 90 engaged in HIIT, and 30 engaged in moderate-intensity continuous training (MICT). High-intensity interval training included 4 to 8 alternating intervals of high- (30-60 seconds at a rating of perceived exertion [RPE] of 15-17 [Borg scale range, 6-20]) and low-intensity (1-5 minutes at RPE <14), and MICT performed for 20 to 45 minutes of exercise at an RPE of 12 to 14. Body weight, fat mass, and lean mass were measured via dual-energy x-ray absorptiometry with lipid profile measured via clinical procedures.
The HIIT and MICT groups were similar in age (67 vs 67 years), sex (26.7% [24 of 90 patients in the HIIT group] vs 26.7% [8 of 30 in the MICT group), and body mass index (30.3 vs 29.5 kg/m) at baseline. The HIIT group had greater reductions in body fat percentage (P<.001), fat mass (P<.001), abdominal fat percentage (P<.001), waist circumference (P=.01), total cholesterol (P=.002), low-density lipoprotein cholesterol (P<.001), and triglycerides (P=.006). Improvements in total body mass and body mass index were not different across groups. After matching exercise duration, exercise intensity, and energy expenditure, HIIT-induced improvements in total fat mass (P=.02), body fat percentage (P=.01), and abdominal fat percentage (P=.02) persisted.
Our data suggest that supervised HIIT results in significant reductions in total fat mass (P<.001) and abdominal fat percentage (P<.001) and improved lipid profile in patients with MI who undergo CR.
探讨高强度间歇训练（HIIT）对接受心脏康复（CR）的心肌梗死（MI）患者体脂肪量和分布的影响。
我们回顾性筛选了 2015 年 9 月 1 日至 2018 年 2 月 28 日期间在 CR 中连续接受治疗的 391 例 MI 患者。我们纳入了 120 例完成了 36 次 CR 疗程并接受了预测试后双能 X 射线吸收法检测的患者；其中 90 例进行了 HIIT，30 例进行了中等强度持续训练（MICT）。高强度间歇训练包括 4 到 8 个交替的高（30-60 秒，感知用力程度[RPE]为 15-17 [Borg 量表范围，6-20]）和低强度（1-5 分钟，RPE <14）区间，以及在 RPE 为 12 到 14 时进行 20 到 45 分钟的运动。通过双能 X 射线吸收法测量体重、体脂肪量和瘦体重，并通过临床程序测量血脂谱。
HIIT 组和 MICT 组在年龄（67 岁 vs 67 岁）、性别（26.7%[90 例 HIIT 组中的 24 例] vs 26.7%[30 例 MICT 组中的 8 例]）和身体质量指数（30.3 千克/米）方面基线相似。HIIT 组的体脂肪百分比（P<.001）、体脂肪量（P<.001）、腹部脂肪百分比（P<.001）、腰围（P=.01）、总胆固醇（P=.002）、低密度脂蛋白胆固醇（P<.001）和甘油三酯（P=.006）降低更为显著。两组间的总体重和体重指数的改善没有差异。在匹配运动持续时间、运动强度和能量消耗后，HIIT 引起的总体脂肪量（P=.02）、体脂肪百分比（P=.01）和腹部脂肪百分比（P=.02）的改善仍然存在。
我们的数据表明，在接受 CR 的 MI 患者中，监督下的 HIIT 可显著降低总体脂肪量（P<.001）和腹部脂肪百分比（P<.001），并改善血脂谱。
