T细胞确定了由小鼠1号染色体M1s区域中的一个基因或多个基因控制的新的同种异体抗原。
T cells define new alloantigens controlled by a gene(s) in the M1s region on mouse chromosome 1.
作者信息
Kimura S, Furze J, Festenstein H
机构信息
Department of Immunology, London Hospital Medical College, U.K.
出版信息
J Immunogenet. 1988 Feb-Jun;15(1-3):31-7. doi: 10.1111/j.1744-313x.1988.tb00405.x.
Abstract
Two different types of T cell clones which recognize Mlsb haplotype gene products were established by using mice congenic at the Mls locus. The antigens defined by these T cells showed differences not only in strain distribution but also in the restriction element for antigen recognition by T cells (i.e. Kd or Dd). The antigens appear to be expressed on various types of lymphocytes.
摘要
通过使用在Mls位点基因纯合的小鼠，建立了两种识别Mlsb单倍型基因产物的不同类型的T细胞克隆。这些T细胞所定义的抗原不仅在品系分布上存在差异，而且在T细胞识别抗原的限制元件（即Kd或Dd）方面也有所不同。这些抗原似乎在各种类型的淋巴细胞上表达。
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