小鼠同种异体抗原的Igh连锁基因座Lm-1的鉴定与定位。
Identification and mapping of Lm-1, an Igh-linked locus for a murine alloantigen.
作者信息
O'Toole M M, Riblet R, Bosma M J
出版信息
Immunogenetics. 1984;20(3):265-75. doi: 10.1007/BF00364208.
PMID:6332069
Abstract
Analyzing Igh congenic, Igh recombinant, and recombinant inbred mouse strains with a cytotoxic T-cell assay, we have identified and mapped an Igh-linked locus (Lm-1) that codes for a cell-surface alloantigen (Lm-1). Lm-1 maps 5 units telomeric to Pre-1 and is genetically distinct from previously described Igh-linked loci. The importance of Lm-1 and its possible relationship to other Igh-linked alloantigens is discussed.
摘要
通过细胞毒性T细胞检测分析Igh同源、Igh重组和重组近交小鼠品系，我们鉴定并定位了一个与Igh连锁的基因座（Lm-1），它编码一种细胞表面同种异体抗原（Lm-1）。Lm-1位于Pre-1端粒方向5个单位处，在遗传上与先前描述的与Igh连锁的基因座不同。本文讨论了Lm-1的重要性及其与其他与Igh连锁的同种异体抗原可能的关系。
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