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人工耳蜗植入后早期激活的可行性。

Feasibility of early activation after cochlear implantation.

机构信息

Department of Otolaryngology, Taichung Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Taichung, Taiwan.

School of Medicine, Tzu Chi University, Hualien, Taiwan.

出版信息

Clin Otolaryngol. 2019 Nov;44(6):1004-1010. doi: 10.1111/coa.13427. Epub 2019 Oct 2.

DOI:10.1111/coa.13427
PMID:31487432
Abstract

OBJECTIVES

The purpose of the study is to investigate feasibility of early activation after cochlear implantation by evaluating long-term impedance change and speech perception.

DESIGN

Case-control study SETTING: Between July 2015 and December 2016, we prospectively enrolled 20 subjects for early activation (within 24 hours after cochlear implantation). On the other hand, from November 2013 to July 2015, 20 age- and sex-matched control subjects from the database of cochlear implantees treated with conventional activation schedule (4 weeks after surgery) were retrospectively enrolled.

PARTICIPANT

Forty patients who underwent cochlear implantation surgeries.

MAIN OUTCOME MEASURES

The series impedance and speech perception score of both groups were compared.

RESULTS

No statistical difference in long-term follow-up between the two groups was found using GEEs and multivariate analysis. In the early activation group, impedance reached a steady level by the 2nd postoperative week, and the hearing perception ability significantly improved by the 4th postoperative week.

CONCLUSION

This comparative study illustrated sequential impedance data during early activation (24 hours) and conventional activation (4 weeks) after CI surgery. There were no major complications in either group, and the safety of early activation with respect to impedance changes, postoperative residual hearing preservation and speech perception scores were non-inferior to that of the conventional group. Therefore, in this study, we established the feasibility of early activation 24 hours after cochlear implantation.

摘要

目的

通过评估长期阻抗变化和言语感知,研究耳蜗植入后早期激活的可行性。

设计

病例对照研究

设置

2015 年 7 月至 2016 年 12 月,我们前瞻性地招募了 20 名早期激活(耳蜗植入后 24 小时内)的受试者。另一方面,从 2013 年 11 月至 2015 年 7 月,我们从接受常规激活方案(术后 4 周)治疗的耳蜗植入者数据库中回顾性地招募了 20 名年龄和性别匹配的对照组受试者。

参与者

40 名接受耳蜗植入手术的患者。

主要观察指标

比较两组的系列阻抗和言语感知评分。

结果

使用广义估计方程和多变量分析,两组在长期随访中无统计学差异。在早期激活组,阻抗在术后第 2 周达到稳定水平,听力感知能力在术后第 4 周显著提高。

结论

本对照研究描述了 CI 手术后早期激活(24 小时)和常规激活(4 周)期间的序贯阻抗数据。两组均无重大并发症,早期激活在阻抗变化、术后残余听力保护和言语感知评分方面的安全性不劣于常规组。因此,在这项研究中,我们确定了耳蜗植入后 24 小时内进行早期激活的可行性。

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