早期孕妇血清25-羟维生素D水平与肥胖情况
Serum level of 25-hydroxyvitamin D and obesity among early pregnant women.
作者信息
Mahmoud Sally Z, Saad Alfarazdeg A, Mohieldein Abdelmarouf H, Nasr Abubakr M, Adam Ishag
机构信息
Faculty of Medicine, University of Khartoum, Khartoum, Sudan.
Faculty of Medicine, University of Taibah, Almadinah Almunawwarah, Kingdom of Saudi Arabia.
出版信息
J Obstet Gynaecol Res. 2019 Dec;45(12):2338-2342. doi: 10.1111/jog.14114. Epub 2019 Sep 5.
AIM
To assess serum 25-hydroxyvitamin D 25(OH)D level in obese pregnant Sudanese women in early pregnancy.
METHODS
A match case-control study was conducted in Saad Abualila Hospital (Khartoum, Sudan). The cases were obese (body mass index [BMI] ≥ 30.0 kg/m ) women. Controls were women with normal BMI (18.5-24.9 kg/m ) matched for age, parity and gestational age. The 25(OH)D level was measured using ELISA.
RESULTS
There was no significant difference between the two groups in their age, parity or gestational age. There was no significant difference in the median (interquartile) level of the serum (25(OH)D between obese pregnant women and normal weight pregnant women (3.05 [11.100-15.937] ng/ml vs 13.05 [10.950-17.362] ng/ml, P = 0.237). There was no significant correlation between BMI and 25(OH)D level (r = -0.133, P = 0.149).
CONCLUSION
There was no significant difference in the 25(OH)D level between the obese pregnant women and normal weight pregnant women in this study.
目的
评估苏丹肥胖孕妇孕早期血清25-羟维生素D[25(OH)D]水平。
方法
在苏丹喀土穆的萨阿德·阿布阿利拉医院开展一项匹配病例对照研究。病例组为肥胖（体重指数[BMI]≥30.0kg/m²）女性。对照组为BMI正常（18.5-24.9kg/m²）且年龄、产次和孕周相匹配的女性。采用酶联免疫吸附测定法检测25(OH)D水平。
结果
两组在年龄、产次或孕周方面无显著差异。肥胖孕妇与正常体重孕妇血清25(OH)D的中位数（四分位间距）水平无显著差异（3.05[11.100-15.937]ng/ml对13.05[10.950-17.362]ng/ml，P=0.237）。BMI与25(OH)D水平无显著相关性（r=-0.133，P=0.149）。
结论
本研究中肥胖孕妇与正常体重孕妇的25(OH)D水平无显著差异。
Zotero 插件