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钝性创伤性脾损伤采用保守或手术治疗后的结果

Outcomes Following Blunt Traumatic Splenic Injury Treated with Conservative or Operative Management.

作者信息

Corn Sarah, Reyes Jared, Helmer Stephen D, Haan James M

机构信息

University of Kansas School of Medicine-Wichita, Department of Surgery, Wichita, KS.

Department of Medical Education, Via Christi Hospital Saint Francis, Wichita, KS.

出版信息

Kans J Med. 2019 Aug 21;12(3):83-88. eCollection 2019 Aug.

Abstract

INTRODUCTION

Laparotomy, embolization, and observation are described for blunt splenic injury management. This study evaluated outcomes of blunt splenic injury management based on baseline factors, splenic injury severity, and associated injuries.

METHODS

A nine-year retrospective review was conducted of adult patients with blunt splenic injury. Collected data included demographics, injury characteristics, treatment modality, complications, and outcomes (mechanical ventilation, days on mechanical ventilation, intensive care unit [ICU] admission and length of stay, hospital length of stay, and in-hospital mortality). Categorical and continuous variables were analyzed using χ analysis and one-way analysis of variance for normally distributed variables and a non-parametric test of medians for variables that did not meet the assumption of normality, respectively.

RESULTS

Splenic injury grade was similar between operative and embolization groups, but severe hemoperitoneum was more common in the operative group. Complications and mortality were highest in the operative group (50.7% and 26.3%, respectively) and lowest in the embolization group (5.3% and 2.6%, respectively). Operative patients required more advanced interventions (ICU admission, mechanical ventilation). There were no differences between those treated with proximal versus distal embolization. Observation carried a failure rate of 11.2%, with no failures of embolization.

CONCLUSIONS

Embolization patients had the lowest rates of complications and mortality, with comparable splenic injury grades to those treated operatively. Further prospective research is warranted to identify patients that may benefit from early embolization and avoidance of major abdominal surgery.

摘要

引言

剖腹手术、栓塞术及观察疗法被用于钝性脾损伤的处理。本研究基于基线因素、脾损伤严重程度及相关损伤评估钝性脾损伤的处理结果。

方法

对成年钝性脾损伤患者进行了为期九年的回顾性研究。收集的数据包括人口统计学资料、损伤特征、治疗方式、并发症及结果(机械通气、机械通气天数、重症监护病房[ICU]收治情况及住院时间、住院总时长及院内死亡率)。分类变量和连续变量分别采用χ分析和单因素方差分析,对于正态分布变量采用此方法,对于不符合正态分布假设的变量采用中位数非参数检验。

结果

手术组和栓塞组的脾损伤分级相似,但严重腹腔积血在手术组更为常见。手术组的并发症和死亡率最高(分别为50.7%和26.3%),栓塞组最低(分别为5.3%和2.6%)。手术患者需要更高级别的干预措施(入住ICU、机械通气)。近端栓塞与远端栓塞治疗的患者之间无差异。观察疗法的失败率为11.2%,栓塞术无失败病例。

结论

栓塞治疗患者的并发症和死亡率最低,脾损伤分级与手术治疗患者相当。有必要进行进一步的前瞻性研究,以确定可能从早期栓塞治疗及避免腹部大手术中获益的患者。

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