肝胆外科医生与免疫学家的会面：以结直肠癌肝转移患者为例
Hepatobiliary surgeons meet immunologists: the case of colorectal liver metastases patients.
作者信息
Donadon Matteo, Cortese Nina, Marchesi Federica, Cimino Matteo, Mantovani Alberto, Torzilli Guido
机构信息
Department of Hepatobiliary and General Surgery, Humanitas University, Pieve Emanuele, Italy.
Department of Biomedical Sciences, Humanitas University, Pieve Emanuele, Italy.
出版信息
Hepatobiliary Surg Nutr. 2019 Aug;8(4):370-377. doi: 10.21037/hbsn.2019.03.06.
Abstract
The burgeoning field of cancer immunology demands a change in the paradigm of cancer patient management. The understanding of the course of a given malignant disease should also include the host immune system as one of the key factors in determining the patient's prognosis. Surgical and medical oncologists need to understand the basic and advanced applications of immunotherapies, which are rapidly evolving, and are nowadays an integral part of the armamentarium for the treatment of cancer patients. In the present work, we review the current knowledge concerning the immune landscape of colorectal cancer (CRC) patients with liver metastases, as recently discovered.
摘要
癌症免疫学这一新兴领域要求改变癌症患者的管理模式。对特定恶性疾病病程的理解还应将宿主免疫系统视为决定患者预后的关键因素之一。外科肿瘤学家和医学肿瘤学家需要了解免疫疗法的基础和高级应用，这些应用正在迅速发展，如今已成为治疗癌症患者的重要手段。在本研究中，我们回顾了最近发现的有关伴有肝转移的结直肠癌（CRC）患者免疫状况的现有知识。
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