Service de Chirurgie Urologique, CHU Henri-Mondor, AP-HP, 51 Avenue du Maréchal de Lattre de Tassigny, 94000, Créteil, France.
INSERM U955, Equipe 7, CHU Henri-Mondor, AP-HP, 94000, Créteil, France.
World J Urol. 2020 Jun;38(6):1545-1553. doi: 10.1007/s00345-019-02941-1. Epub 2019 Sep 5.
To report the functional outcomes, perioperative morbidity and surgical learning curve key points using "en bloc" greenlight enucleation of prostate (EB-GreenLEP) for patients with refractory lower urinary tract symptoms (LUTS) due to benign prostatic hyperplasia (BPH).
Between December, 2015 and May, 2018, all consecutive patients with refractory LUTS due to BPH in our institution were included and underwent EB-GreenLEP by a single surgeon. Perioperative data, complications and functional outcomes at 1-, 6- and 12-month follow-ups were collected and retrospectively analyzed.
One hundred patients were included whose median age was 69 years. The median prostate volume (PV) was 84 mL and median enucleated PV was 45.5 mL. Mean irrigation, catheterization and hospitalization times were 1.3, 1.4 and 1.6 days, respectively. Average follow-up was 9.3 months. A single high-grade Clavien-Dindo complication occurred. No urinary retention was reported. Two conversions to conventional resection of the prostate were noted. Three patients had postoperative urinary incontinence at 6 months, only one at 1 year (1%). At 1, 6 and 12 months, there was a significant improvement in IPSS score, QoL and Q. Enucleation and energy efficiency ratios were shorter after the 30th procedure. We demonstrated a linear correlation between enucleation time and PV (r = 0.53, p < 0.0001).
Our study shows that the mid-term functional results of EB-GreenLEP are comparable to other laser sources for the endoscopic enucleation of the prostate but with a shorter learning curve. We showed that, with (a) low rates of complications and a short hospital stay, EB-GreenLEP can manage medium-size glands (60-90 mL).
报告使用“整块”绿激光前列腺切除术(EB-GreenLEP)治疗因前列腺增生(BPH)导致难治性下尿路症状(LUTS)患者的功能结果、围手术期发病率和手术学习曲线要点。
2015 年 12 月至 2018 年 5 月,我院所有因 BPH 导致难治性 LUTS 的连续患者均由一名外科医生行 EB-GreenLEP。收集并回顾性分析围手术期数据、并发症和术后 1、6 和 12 个月的功能结果。
共纳入 100 例患者,中位年龄 69 岁。前列腺体积(PV)中位数为 84ml,切除的 PV 中位数为 45.5ml。平均冲洗、置管和住院时间分别为 1.3、1.4 和 1.6 天。平均随访 9.3 个月。仅发生 1 例高分级 Clavien-Dindo 并发症。无尿潴留报道。有 2 例转为常规前列腺切除术。术后 6 个月有 3 例出现尿失禁,术后 1 年仅 1 例(1%)。术后 1、6 和 12 个月,国际前列腺症状评分(IPSS)、生活质量(QoL)和 Q 均显著改善。第 30 次手术后,切除时间和能量效率比更短。我们发现切除时间与 PV 之间存在线性相关性(r=0.53,p<0.0001)。
我们的研究表明,EB-GreenLEP 的中期功能结果与其他激光源的前列腺内镜切除术相当,但学习曲线更短。我们表明,EB-GreenLEP 可在(a)低并发症发生率和短住院时间的情况下,处理 60-90ml 的中等大小腺体。