全球、区域和国家层面 2018 年 90-90-90 目标估计数：评估实现 2020 年目标的进展情况。

Global, regional and country-level 90-90-90 estimates for 2018: assessing progress towards the 2020 target.

机构信息

aStrategic Information Department, The Joint United Nations Programme on HIV/AIDS (UNAIDS), Geneva, Switzerland bDepartment of Infectious Disease Epidemiology, Imperial College London, St Mary's Hospital, London, UK.

出版信息

AIDS. 2019 Dec 15;33 Suppl 3(Suppl 3):S213-S226. doi: 10.1097/QAD.0000000000002355.

DOI:10.1097/QAD.0000000000002355

PMID:31490781

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6919229/

Abstract

BACKGROUND

In 2014, the Joint United Nations Programme on HIV/AIDS (UNAIDS) and partners set the 90-90-90 target for the year 2020: diagnose 90% of all people living with HIV (PLHIV); treat 90% of people who know their status; and suppress the virus in 90% of people on treatment. In 2015, countries began reporting to UNAIDS on progress against 90-90-90 using standard definitions and methods.

METHODS

We used data submitted to UNAIDS from 170 countries to assess country-specific progress towards 90-90-90 through 2018. To assess global and regional progress, overall and by sex for adults aged 15 years and older, we combined country-reported data with estimates generated with a Bayesian hierarchical model.

RESULTS

A total of 60 countries reported on all three 90s in 2018, up from 23 in 2015. Among all PLHIV worldwide, 79% (67-92%) knew their HIV status. Of these, 78% (69-82%) were accessing treatment and 86% (72-92%) of people accessing treatment had suppressed viral loads. Of the 37.9 million (32.7-44.0 million) PLHIV worldwide, 53% (43-63%) had suppressed viral loads. The gap to fully achieving 73% of PLHIV with suppressed viral load was 7.7 million; 15 countries had already achieved this target by 2018.

CONCLUSION

Increased data availability has led to improved measures of country and global progress towards the 90-90-90 target. Although gains in access to testing and treatment continue, many countries and regions are unlikely to reach the 90-90-90 target by 2020.

摘要

背景

2014 年，联合国艾滋病规划署（UNAIDS）及其合作伙伴为 2020 年设定了 90-90-90 目标：诊断所有艾滋病毒感染者（PLHIV）的 90%；知晓自身状况的 90%PLHIV接受治疗；接受治疗的 90%PLHIV病毒得到抑制。2015 年，各国开始根据标准定义和方法向 UNAIDS 报告实现 90-90-90 的进展情况。

方法

我们使用从 170 个国家向 UNAIDS 提交的数据，通过 2018 年评估各国在实现 90-90-90 目标方面的具体进展。为了评估全球和区域进展情况，我们将国家报告的数据与贝叶斯层次模型生成的估计数据相结合，按年龄在 15 岁及以上的成年人进行了总体和性别分类评估。

结果

共有 60 个国家在 2018 年报告了所有三个 90%的目标，高于 2015 年的 23 个。在全球所有 PLHIV 中，79%（67-92%）知晓其 HIV 状况。其中，78%（69-82%）正在接受治疗，86%（72-92%）接受治疗的人病毒载量得到抑制。在全球 3790 万（3270-4400 万）PLHIV 中，53%（43-63%）的病毒载量得到抑制。要使 73%的 PLHIV 病毒载量得到完全抑制，还有 770 万人的差距；到 2018 年，已有 15 个国家达到了这一目标。