佐剂性关节炎大鼠的腹腔巨噬细胞在体外可促进肿瘤细胞生长。
Peritoneal macrophages from adjuvant arthritic rats enhance tumour cell growth in vitro.
作者信息
Binderup L, Bramm E, Arrigoni-Martelli E
出版信息
Experientia. 1979 Sep 15;35(9):1230-2. doi: 10.1007/BF01963307.
PMID:314909
Abstract
Peritoneal macrophages from rats with adjuvant arthritis enhance the incorporation of 3H-thymidine in 2 tumour cell lines in vitro. Maximal enhancement is found during the development of the secondary lesions, and it is suggested that the immunologic commitment of the macrophages could interfere with their regulation of tumour cell proliferation in vivo.
摘要
佐剂性关节炎大鼠的腹腔巨噬细胞可增强两种肿瘤细胞系在体外对3H-胸腺嘧啶核苷的摄取。在继发性病变发展过程中发现最大增强效应，提示巨噬细胞的免疫趋向性可能会干扰其在体内对肿瘤细胞增殖的调控。
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