Harpale Kashmira, Jagtap Krishna, Bankar Ashok, Dhole Sanjay, More Mahendra
Centre for Advanced Studies in Material Science and Condensed Matter Physics, Department of Physics, Savitribai Phule Pune University, Pune 411007, India.
Department of Microbiology, MES-Abasaheb Garware College (S.P. Pune University), Pune 411005, India.
J Nanosci Nanotechnol. 2020 Apr 1;20(4):2639-2644. doi: 10.1166/jnn.2020.17367.
A nanocomposite of Polypyrrole (PPy) and zinc oxide (ZnO), termed as PPy-ZnO, was synthesized by two step route. In the first step, synthesis of PPy was carried out by chemical oxidative route. In the second step, the PPy-ZnO nanocomposite was synthesized under hydrothermal conditions. The as-synthesized PPy-ZnO nanocomposites were characterized using X-ray Diffraction (XRD), scanning electron microscopy (SEM), Fourier Transform Infra-red (FTIR) and Ultra violetvisible (UV-vis) spectroscopy to reveal the phase, morphology, chemical and optical properties. The physical and chemical characterizations confirmed presence of both PPy and ZnO phases in the nanocomposite. In the present work, antimicrobial activity of the PPy-ZnO nanocomposite against human pathogen has been investigated. Attempts have been made to reveal the influence of PPy percentage on the antimicrobial activity. Interestingly, all PPy-ZnO nanocomposites, irrespective of PPy percentage, showed 90 to 95% inhibited growth of . The results obtained herein imply the potential of PPy-ZnO biofilm in inhibiting the growth of and thus preventing infections caused due to in humans.
一种由聚吡咯(PPy)和氧化锌(ZnO)组成的纳米复合材料,称为PPy-ZnO,通过两步法合成。第一步,通过化学氧化法合成PPy。第二步,在水热条件下合成PPy-ZnO纳米复合材料。使用X射线衍射(XRD)、扫描电子显微镜(SEM)、傅里叶变换红外(FTIR)和紫外可见(UV-vis)光谱对合成的PPy-ZnO纳米复合材料进行表征,以揭示其相、形态、化学和光学性质。物理和化学表征证实了纳米复合材料中同时存在PPy和ZnO相。在本工作中,研究了PPy-ZnO纳米复合材料对人类病原体的抗菌活性。已尝试揭示PPy百分比对抗菌活性的影响。有趣的是,所有PPy-ZnO纳米复合材料,无论PPy百分比如何,均显示出90%至95%的[病原体名称]生长抑制率。本文获得的结果表明PPy-ZnO生物膜在抑制[病原体名称]生长以及预防人类因[病原体名称]引起的感染方面具有潜力。