Orthopedic and Spinal Surgery Department, Kingdom Hospital, P.O. Box 84400, Riyadh, 11671, Saudi Arabia.
Orthopedic Spinal Surgery Unit 1, Bordeaux Pellegrin Hospital, Bordeaux, France.
Eur Spine J. 2020 Jan;29(1):73-84. doi: 10.1007/s00586-019-06141-8. Epub 2019 Sep 6.
To assess pain, health-related quality of life (HRQOL) scores and sagittal parameters of adult spinal deformity (ASD)-operated patients in the context of their analgesic consumption especially opioids (narcotics) over the first year postoperative period.
In total, 372 patients from a multicenter database were stratified into 3 groups at baseline: 241 patients in the minimal group (no analgesic, or NSAIDs/narcotics weekly or less), 64 in the NSAIDs every day group and 67 in the narcotics every day group. HRQOL and back and leg pain scores were evaluated at 6 months and 1 year postoperatively. Also several sagittal alignment parameters were assessed.
Significant improvements in pain and HRQOL scores were observed across all 3 groups by 1 year (P < 0.05) postoperatively. While the minimal group had the best pre- and postoperative HRQOL scores, the NSAID group demonstrated the best improvement in HRQOL. Only the minimal group displayed continued improvement from 6 months to 1 year. 90%, 65% and 40% of minimal, NSAID and narcotic groups of patients, respectively, no longer took any analgesics at 1 year postoperatively. Alternatively, 36% of patients in the narcotics group continued to take narcotics at 1 year. Residual malalignment increased NSAIDs consumption in different groups at 1 year.
This study evaluated the analgesics use after ASD surgery in relation to the clinical and radiological outcomes. Despite important postoperative opioids consumption in the narcotics group, clinical outcome yet improved. Malalignment parameters demonstrated a predictive value in regard to NSAIDs' usage. These slides can be retrieved under Electronic Supplementary Material.
评估成人脊柱畸形(ASD)术后患者在术后第一年的镇痛药物(特别是阿片类药物)消耗情况下的疼痛、健康相关生活质量(HRQOL)评分和矢状参数。
总共对来自多中心数据库的 372 名患者进行了基线分层,分为 3 组:最小组(无镇痛药物,或每周使用非甾体抗炎药/阿片类药物少于或等于 1 次)241 例,每天使用 NSAIDs 组 64 例,每天使用阿片类药物组 67 例。术后 6 个月和 1 年时评估 HRQOL 和腰背腿痛评分。同时评估了几个矢状面参数。
术后 1 年时,所有 3 组的疼痛和 HRQOL 评分均有显著改善(P<0.05)。虽然最小组的术前和术后 HRQOL 评分最好,但 NSAID 组的 HRQOL 改善最佳。只有最小组的 HRQOL 评分从术后 6 个月持续改善至 1 年。最小、NSAID 和阿片类药物组分别有 90%、65%和 40%的患者在术后 1 年时不再使用任何镇痛药物。而阿片类药物组中有 36%的患者在术后 1 年时仍继续使用阿片类药物。残留的不匹配在不同组中增加了 NSAIDs 的使用在术后 1 年。
本研究评估了 ASD 手术后阿片类药物的使用与临床和影像学结果的关系。尽管阿片类药物组患者术后阿片类药物的消耗仍然很高,但临床结果仍有改善。失平衡参数在 NSAIDs 的使用方面具有预测价值。这些幻灯片可以在电子补充材料中找到。