Son Seung-Myoung, Woo Chang Gok, Lee Ok-Jun, Lee Sang-Jeon, Lee Taek-Gu, Lee Ho-Chang
Department of Pathology, Chungbuk National University Hospital, Cheongju, Republic of Korea.
Chungbuk National University College of Medicine, Cheongju, Republic of Korea.
J Int Med Res. 2019 Oct;47(10):4827-4840. doi: 10.1177/0300060519862055. Epub 2019 Sep 9.
The aim of this study was to identify clinicopathological factors that affect the number of lymph nodes (LNs) (12 or more) retrieved from patients with colorectal cancer (CRC), particularly those with pathologic T1 (pT1) disease.
From 429 CRC patients, 75 pT1 cancers were identified and digitally scanned. Binary logistic regression analysis was performed to identify the clinicopathological factors affecting the number of LNs retrieved from all 429 patients and from the subset of patients with pT1 CRC.
For the 429 patients, the mean number of harvested LNs per specimen was 20 (median, 19). The number of retrieved LNs was independently associated with maximum tumor diameter > 2.3 cm and right-sided tumor location. The mean number of LNs retrieved from the 75 patients with pT1 CRC was 14 (median, 15); retrieval of 12 or more LNs from this group was independently associated with maximum tumor diameter > 14.1 mm.
The number of LNs retrieved from patients with CRC was associated with maximum tumor diameter and right-sided tumor location. For patients with pT1 CRC, maximum tumor diameter was independently associated with the harvesting of 12 or more LNs.
本研究旨在确定影响从结直肠癌（CRC）患者，尤其是病理T1（pT1）期疾病患者中获取的淋巴结（LN）数量（12个或更多）的临床病理因素。
从429例CRC患者中识别出75例pT1期癌症，并进行数字扫描。进行二元逻辑回归分析，以确定影响从所有429例患者以及pT1期CRC患者亚组中获取的LN数量的临床病理因素。
对于429例患者，每个标本收获的LN平均数量为20个（中位数为19个）。获取的LN数量与最大肿瘤直径>2.3 cm以及肿瘤位于右侧独立相关。从75例pT1期CRC患者中获取的LN平均数量为14个（中位数为15个）；从该组中获取12个或更多LN与最大肿瘤直径>14.1 mm独立相关。
从CRC患者中获取的LN数量与最大肿瘤直径和肿瘤位于右侧有关。对于pT1期CRC患者，最大肿瘤直径与获取12个或更多LN独立相关。
