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环境乙醇对黑腹果蝇辛醇脱氢酶基因座基因频率的影响。

Changes in gene frequencies at the octanol dehydrogenase locus of Drosophila melanogaster imposed by environmental ethanol.

作者信息

Pecsenye K, Lörincz G

机构信息

Department of Zoology and Anthropology, Kossuth Lajos University, Debrecen, Hungary.

出版信息

Genetica. 1988 Nov 30;77(3):171-7. doi: 10.1007/BF00122387.

DOI:10.1007/BF00122387
PMID:3149601
Abstract

Experiments have been performed to study the effect of selection at the Odh locus in Drosophila melanogaster populations using different alcohol concentrations in the medium. The data can be best interpreted by assuming frequency-dependent selection. When genotype frequencies are considered as independent variables and values of Wrightian fitness as dependent variables, it turns out that different functions describe the selection of the coexisting genotypes. A linear equation is used for the SF genotype and a hyperbolic function for the FF genotype. No function of good fit could be found for the SS genotype. Simulation experiments using these functions fit our data well.

摘要

已进行实验以研究在培养基中使用不同酒精浓度时,黑腹果蝇群体中Odh基因座的选择效应。通过假设频率依赖选择可以最好地解释这些数据。当将基因型频率视为自变量,而赖特适应性值视为因变量时,结果发现不同的函数描述了共存基因型的选择。对于SF基因型使用线性方程,对于FF基因型使用双曲线函数。未找到适用于SS基因型的拟合良好的函数。使用这些函数的模拟实验很好地拟合了我们的数据。

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Genetica. 1988 Nov 30;77(3):171-7. doi: 10.1007/BF00122387.
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本文引用的文献

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FREQUENCY-DEPENDENT MATING IN A MODIFIED ALLOZYME LOCUS OF DROSOPHILA PSEUDOOBSCURA.拟暗果蝇一个修饰的等位酶基因座中的频率依赖性交配
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MULTIGENIC RESPONSE TO ETHANOL IN DROSOPHILA MELANOGASTER.黑腹果蝇对乙醇的多基因反应。
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A Study of Frequency-Dependent Selection Observed in the Esterase-6 Locus of DROSOPHILA MELANOGASTER Using a Conditioned Media Method.使用条件培养基法对黑腹果蝇酯酶-6基因座中频率依赖性选择的研究。
Genetics. 1971 May;68(1):97-104. doi: 10.1093/genetics/68.1.97.
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The genetic control of alcohol dehydrogenase and octanol dehydrogenase isozymes in Drosophila.果蝇中乙醇脱氢酶和辛醇脱氢酶同工酶的遗传控制
Genetics. 1966 Nov;54(5):1251-60. doi: 10.1093/genetics/54.5.1251.
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FREQUENCY-DEPENDENT SELECTION AT THE ESTERASE 6 LOCUS IN Drosophila melanogaster.黑腹果蝇酯酶6位点的频率依赖型选择
Proc Natl Acad Sci U S A. 1967 Mar;57(3):645-9. doi: 10.1073/pnas.57.3.645.
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Single-gene heterosis in Drosophila revealed by inbreeding.近亲繁殖揭示果蝇中的单基因杂种优势。
Nature. 1971 Sep 10;233(5315):123-5. doi: 10.1038/233123a0.
8
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Biochem Genet. 1982 Aug;20(7-8):681-8. doi: 10.1007/BF00483965.
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Biochem Genet. 1980 Oct;18(9-10):905-13. doi: 10.1007/BF00500123.