AlDallal Salma M
Haematology & Blood Bank Department, Amiri Hospital, Kuwait Ministry of Health, Sharq, Kuwait.
Int J Gen Med. 2019 Aug 13;12:279-282. doi: 10.2147/IJGM.S217369. eCollection 2019.
Sickle cell disease (SCD) is a group of inherited blood disorders recognized by WHO as a major public health problem. It affects morbidity and mortality of the affected population considerably. Leg ulcer in the lower limbs is a hallmark feature of SCD. Meticulous physical examination, thorough history, laboratory tests, and imaging will lead to proper diagnosis and lead to proper treatment and management of the cases. Although newer treatment strategies have improved the prognostic outcome of SCD, leg ulcers still are a disabling and difficult to treat a complication of the condition. This mini review summarizes this common complication of SCD.
镰状细胞病（SCD）是一组遗传性血液疾病，被世界卫生组织认定为一个重大的公共卫生问题。它对受影响人群的发病率和死亡率有相当大的影响。下肢腿部溃疡是镰状细胞病的一个标志性特征。细致的体格检查、详尽的病史询问、实验室检查以及影像学检查将有助于做出正确诊断，并对病例进行恰当的治疗和管理。尽管新的治疗策略改善了镰状细胞病的预后，但腿部溃疡仍然是该病症一种致残且难以治疗的并发症。本综述总结了镰状细胞病的这一常见并发症。
