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健康非裔美国成年人的热觉和机械觉定量感觉测试值。

Thermal and mechanical quantitative sensory testing values among healthy African American adults.

作者信息

Powell-Roach Keesha L, Yao Yingwei, Rutherford Julienne N, Schlaeger Judith M, Patil Crystal L, Suarez Marie L, Shuey David, Angulo Veronica, Carrasco Jesus, Ezenwa Miriam O, Fillingim Roger B, Wang Zaijie J, Molokie Robert E, Wilkie Diana J

机构信息

Department of Community Dentistry and Behavioral Science, College of Dentistry, University of Florida, Gainesville, FL, USA.

Department of Biobehavioral Nursing Science, College of Nursing, University of Florida, Gainesville, FL, USA.

出版信息

J Pain Res. 2019 Aug 9;12:2511-2527. doi: 10.2147/JPR.S211855. eCollection 2019.

Abstract

PURPOSE

Only a few studies have reported quantitative sensory testing (QST) reference values for healthy African Americans, and those studies are limited in sample size and age of participants. The study purpose was to characterize QST values in healthy, pain-free African American adults and older adults whose prior pain experiences and psychological status were also measured. We examined the QST values for differences by sex, age, and body test site.

PATIENTS AND METHODS

A cross-sectional sample of 124 pain-free African American adults (age 18-69 years, 49% female) completed demographic and self-reported pain, fatigue and psychosocial measures. QST was performed to obtain thermal and mechanical responses and associated pain intensity levels.

RESULTS

We found thermal detection values at the anterior forearm were (29.2 °C±1.6) for cool detection (CD) and (34.5 °C±1.2) for warm detection (WD). At that site the sample had cold pain threshold (CPTh) (26.3 °C±5.0), heat pain threshold (HPTh) (37.8 °C±3.6), and mechanical pain thresholds (MPTH) (16.7±22.2 grams of force, gF). There was a significant between sex difference for WD, with women being more sensitive (q=0.027). Lower body sites were less sensitive than upper body sites across all thermal modalities (q<0.003), but not for the mechanical modality.

CONCLUSION

The QST values from this protocol at the anterior forearm indicate that the healthy African American adults had average thermal pain thresholds close to the temperature of adaptation and average MPTh under 20 gF. Differences in responses to thermal and mechanical stimuli for upper verses lower body were consistent with prior research.

摘要

目的

仅有少数研究报告了健康非裔美国人的定量感觉测试(QST)参考值,且这些研究在样本量和参与者年龄方面存在局限性。本研究的目的是描述健康、无疼痛的非裔美国成年人及老年人的QST值,同时测量他们既往的疼痛经历和心理状态。我们研究了QST值在性别、年龄和身体测试部位方面的差异。

患者与方法

选取124名无疼痛的非裔美国成年人(年龄18 - 69岁,49%为女性)作为横断面样本,完成人口统计学及自我报告的疼痛、疲劳和心理社会测量。进行QST以获得热和机械反应以及相关的疼痛强度水平。

结果

我们发现前臂前部的冷觉检测(CD)热检测值为(29.2℃±1.6),温觉检测(WD)热检测值为(34.5℃±1.2)。在该部位,样本的冷痛阈值(CPTh)为(26.3℃±5.0),热痛阈值(HPTh)为(37.8℃±3.6),机械痛阈值(MPTH)为(16.7±22.2克力,gF)。WD存在显著的性别差异,女性更敏感(q = 0.027)。在所有热觉模式下,身体下部部位比上部部位敏感性更低(q < 0.003),但在机械觉模式下并非如此。

结论

该方案在前臂前部的QST值表明,健康非裔美国成年人的平均热痛阈值接近适应温度,平均MPTh低于20 gF。上下身对热和机械刺激反应的差异与先前研究一致。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2366/6693422/105b20f1caca/JPR-12-2511-g0001.jpg

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